Results 41 to 50 of about 139,014 (175)

TL1A promotes the postoperative cognitive dysfunction in mice through NLRP3‐mediated A1 differentiation of astrocytes

CNS Neuroscience & Therapeutics, 2023
We investigated the mechanism, whereby tumor necrosis factor‐like ligand 1A (TL1A) mediates the A1 differentiation of astrocytes in postoperative cognitive dysfunction (POCD).
Genghuan Wang, Jian Shen, L. Zhai, Yingcong Lin, Q. Guan, Heping Shen   +5 more
semanticscholar   +1 more source

Postoperative Cognitive Dysfunction

Open Access Indonesian Journal of Medical Reviews, 2021
The impact of general anesthesia on cognitive impairment is controversial and complex. A large body of evidence supports the association between exposure to surgery under general anesthesia and the development of delayed neurocognitive recovery in a subset of patients.
openaire   +2 more sources

Hyperbaric oxygen preconditioning improves postoperative cognitive dysfunction by reducing oxidant stress and inflammation

Neural Regeneration Research, 2017
Postoperative cognitive dysfunction is a crucial public health issue that has been increasingly studied in efforts to reduce symptoms or prevent its occurrence. However, effective advances remain lacking.
Zhi-xin Gao, Jin Rao, Yuan-hai Li
doaj   +1 more source

Minocycline Attenuates Sevoflurane-Induced Postoperative Cognitive Dysfunction in Aged Mice by Suppressing Hippocampal Apoptosis and the Notch Signaling Pathway-Mediated Neuroinflammation

Brain Science, 2023
Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients.
Junjie Liang, Shanshan Han, Chao Ye, Haimeng Zhu, Jia-jun Wu, Yunjuan Nie, Gao-shang Chai, P. Zhao, Deng-xin Zhang   +8 more
semanticscholar   +1 more source

The effect of intravenous lidocaine on postoperative cognitive dysfunction: a systematic review and meta-analysis

BMC Anesthesiology, 2023
Background Postoperative cognitive dysfunction (POCD) has been reported as a significant complication in elderly patients. Various methods have been proposed for reducing the incidence and severity of POCD.
Chuan Geng, Baoji Hu, Jihong Jiang, Yunhe Zhang, Weiqing Tang, Mengzhi Pan, Leilei Sun, Peifen Chen, Hengyue Wang   +8 more
semanticscholar   +1 more source

Effects of total intravenous anesthesia with etomidate and propofol on postoperative cognitive dysfunction.

Physiological Research, 2023
Increased incidence of postoperative cognitive dysfunction (POCD) is observed in elderly patients underwent intravenous anesthesia (TIVA) with endotracheal intubation. Modulation of anesthetics compatibility may reduce the severity of POCD.
Y. Zhi, W. Li
semanticscholar   +1 more source

Postoperative cognitive dysfunction – is it a problem for the anesthesiologist-intensivist?

Вестник анестезиологии и реаниматологии, 2019
Postoperative cognitive dysfunction is a cognitive impairment developing in the postoperative period and confirmed by the data of neuropsychological testing. The article presents the results of a survey among practicing anesthesiologists-resuscitators in
Y. S. Aleksandrovich, T. I. Akimenko, K. V. Pshenisnov   +2 more
doaj   +1 more source

Effectiveness of dual-task computerized cognitive training in the prevention of postoperative cognitive dysfunction in coronary bypass surgery

Кардиоваскулярная терапия и профилактика, 2022
Aim. To evaluate the effectiveness of dual-task computerized cognitive training (CCT) in the prevention of postoperative cognitive dysfunction in patients after on-pump coronary artery bypass grafting (CABG).Material and methods.
O. A. Trubnikova, I. V. Tarasova, I. N. Kukhareva, T. B. Temnikova, A. S. Sosnina, I. D. Syrova, D. S. Kupriyanova, O. I. Barbarash   +7 more
doaj   +1 more source

Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients undergoing orthopaedic surgery: study protocol for a randomized controlled trial

Trials, 2023
Aims This trial aims to assess whether dexmedetomidine can reduce the incidence of postoperative cognitive dysfunction in elderly orthopaedic patients and explore the specific mechanism.
Weihong Zhao, Huanhuan Zhang, Jianli Li
doaj   +1 more source

Activation of astrocyte Gq pathway in hippocampal CA1 region attenuates anesthesia/surgery induced cognitive dysfunction in aged mice

Frontiers in Aging Neuroscience, 2022
The elderly are particularly vulnerable to brain dysfunction after fracture surgery, but the mechanism underlying the cognitive decline due to anesthesia/surgery is not well understood.
Xupeng Wang, Yanan Li, Juan Zhao, Jiaxu Yu, Qi Zhang, Qi Zhang, Fang Xu, Yahui Zhang, Qi Zhou, Chunping Yin, Zhiyong Hou, Zhiyong Hou, Qiujun Wang   +12 more
doaj   +1 more source