Results 41 to 50 of about 39,025 (182)

Electroacupuncture relieves postoperative cognitive dysfunction in elderly rats via regulating amp-activated protein kinase autophagy signaling

Chinese Journal of Physiology, 2022
Postoperative cognitive dysfunction (POCD) is a common complication after surgery in elderly patients. Electroacupuncture (EA) has been reported to relieve POCD in animal models, but the mechanism remains fully elucidated.
Cong Niu, Meihua Zhu, Jiamin Zhang, Chenye Zhang, Weiqian Tian   +4 more
doaj   +1 more source

An Update on Postoperative Cognitive Dysfunction [PDF]

Advances in Anesthesia, 2010
Numerous studies over the past decade have reported an acute change in cognitive status in adult patients after major surgery. Most evidence suggests that these early cognitive changes are transitory and do not persist in the long term. However, the prognostic significance of POCD remains a hotly debated topic, especially in light of recent data ...
Tiffany L, Tsai, Laura P, Sands, Jacqueline M, Leung   +2 more
openaire   +2 more sources

The Impact of Anesthesia Method on Postoperative Cognitive Functions in Urological Surgeries: A Prospective Randomized Single-Blind Study

Van Tıp Dergisi, 2023
INTRODUCTION: Postoperative cognitive dysfunction contributes to cognitive impairments following surgeries.Despite the potential of anesthesia methods causing cognitive dysfunction,conclusive evidence remains elusive.This study aims to compare the ...
Nurettin Kurt
doaj   +1 more source

Postoperative cognitive dysfunction – current preventive strategies

Clinical Interventions in Aging, 2018
Improving trends in global health care have resulted in a steady increase in the geriatric population. However, as the population ages, surgery is being performed more frequently in progressively older patients and those with higher prevalence of comorbidities.
Kotekar N, Shenkar A, Nagaraj R
openaire   +4 more sources

The role of dexmedetomidine administered via intravenous infusion as adjunctive therapy to mitigate postoperative delirium and postoperative cognitive dysfunction in elderly patients undergoing regional anesthesia: a meta-analysis of randomized controlled trials

BMC Anesthesiology
Study objective This meta-analysis aimed to assess whether continuous intravenous administration of DEX during surgery can be part of the measures to prevent the onset of postoperative delirium and postoperative cognitive dysfunction in elderly ...
Di Wang, Xiao He, Zicen Li, He Tao, Congjie Bi   +4 more
doaj   +1 more source

Postoperative Cognitive Dysfunction and Noncardiac Surgery

Anesthesia & Analgesia, 2018
Postoperative cognitive dysfunction (POCD) is an objectively measured decline in cognition postoperatively compared with preoperative function. POCD has been considered in the anesthetic and surgical literature in isolation of cognitive decline which is common in the elderly within the community and where it is labeled as mild cognitive impairment ...
Lisbeth A, Evered, Brendan S, Silbert
openaire   +3 more sources

Biomarkers of postoperative delirium and cognitive dysfunction

Frontiers in Aging Neuroscience, 2015
Elderly surgical patients frequently experience postoperative delirium (POD) and the subsequent development of postoperative cognitive dysfunction (POCD).
Ganna eAndrosova, Roland eKrause, Georg eWinterer, Reinhard eSchneider   +3 more
doaj   +1 more source

Effect of Preoperative Dexmedetomidine on Prevalence of Postoperative Cognitive Dysfunction in Elderly Patients Candidate for Orthopedic Surgery under General Anesthesia

Archives of Anesthesia and Critical Care, 2020
Background: Postoperative cognitive dysfunction (POCD) is amongst the most critical complications after surgery. This study shows the effect of dexmedetomidine on the prevalence of postoperative cognitive impairment.
Alireza Pournajafian, Ali Khatibi, Mohammad Reza Ghodraty, Azadeh Emami, Mona Haji Aghajani   +4 more
doaj   +1 more source

Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials

European Journal of Medical Research
Background Dexmedetomidine plays a pivotal role in mitigating postoperative delirium and cognitive dysfunction while enhancing the overall quality of life among surgical patients.
Di Wang, Zhi Liu, Wenhui Zhang, Guo Zu, He Tao, Congjie Bi   +5 more
doaj   +1 more source

Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll‐like receptor 4 signaling in aged mice

Kaohsiung Journal of Medical Sciences, 2020
Our study aimed to explore the molecular mechanisms involved in the improvement of postoperative cognitive dysfunction (POCD) by dexmedetomidine (DEX).
Xue‐Yue Zhou, Jing Liu, Zhi‐Peng Xu, Qiang Fu, Pei‐Qi Wang, Jing‐Hua Wang, Hong Zhang   +6 more
doaj   +1 more source