Results 51 to 60 of about 139,014 (175)

Obesity and Postoperative Cognitive Dysfunction: A Curious Association

Cureus, 2023
Postoperative cognitive dysfunction (POCD) is a medical condition that impacts cognitive function after surgery, particularly major procedures. Patients with POCD may experience physical symptoms, such as depression, anxiety, and fatigue, severely ...
Camden I Burns, Anto Boghokian, V. Soti
semanticscholar   +1 more source

Muscle Injury Induces Postoperative Cognitive Dysfunction [PDF]

Scientific Reports, 2020
AbstractPostoperative cognitive dysfunction (POCD) is a major complication affecting patients of any age undergoing surgery. This syndrome impacts everyday life up to months after hospital discharge, and its pathophysiology still remains unclear. Translational research focusing on POCD is based on a wide variety of rodent models, such as the murine ...
Lorna Guéniot, Lorna Guéniot, Lorna Guéniot, Pierre L. Goossens, Marine Le Dudal, Patricia Flamant, Gabriela Ferreira de Medeiros, Victoria Lepere, Victoria Lepere, Victoria Lepere, Grégory Jouvion, Grégory Jouvion, Olivier Langeron, Olivier Langeron, Anne Danckaert, Fabrice Chrétien, Fabrice Chrétien   +16 more
openaire   +3 more sources

Adverse postoperative cognitive disorders: a national survey of portuguese anesthesiologists [PDF]

Revista Brasileira de Anestesiologia, 2018
Background and objectives Postoperative delirium and postoperative cognitive dysfunction are some of the most common complications in older surgical patients and are associated with adverse outcomes.
Maria J. Susano, Liliana Vasconcelos, Tiago Lemos, Pedro Amorim, Fernando J. Abelha   +4 more
doaj   +4 more sources

Postoperative cognitive dysfunction: etiology, clinical features, diagnosis

Медицинский совет, 2021
Introduction. The present study analyzed the possibility of using neuropsychological tests to assess postoperative cognitive dysfunction. New data were obtained: in the postoperative period, hippocampal memory impairments predominate in patients, which ...
S. P. Bordovsky, P. M. Krupenin, A. I. Rozen, G. Yu. Evzikov, Y. V. Kirichuk, D. Fantalis, I. S. Preobrazhenskaya   +6 more
doaj   +1 more source

mtDNA-cGAS-STING axis-dependent NLRP3 inflammasome activation contributes to postoperative cognitive dysfunction induced by sevoflurane in mice

International Journal on Biological Sciences
The activation of NLRP3 inflammasome in microglia is critical for neuroinflammation during postoperative cognitive dysfunction (POCD) induced by sevoflurane.
Nan-Shi-Yu Yang, W. Zhong, Han-Xi Sha, Chen-Yu Zhang, Ling Jin, J. Duan, Jian-Bing Xiong, Zhi-Jian You, Yong Zhou, C. Guan   +9 more
semanticscholar   +1 more source

Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice

Frontiers in Aging Neuroscience, 2022
Postoperative cognitive dysfunction (POCD) is a disturbing neurological complication in patients undergoing anesthesia and surgical procedures. Brain-derived neurotrophic factor (BDNF) and its precursor proBDNF binding to their corresponding receptors ...
Zi-Yi Xue, Min Shui, Xiaowan Lin, Yi Sun, Jianhui Liu, Changwei Wei, Anshi Wu, Tianzuo Li   +7 more
semanticscholar   +1 more source

Activation of the Lateral Habenula‐Ventral Tegmental Area Neural Circuit Contributes to Postoperative Cognitive Dysfunction in Mice

Advancement of science, 2022
Postoperative cognitive dysfunction (POCD) is common and is associated with poor outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that regulates coping and depression‐like behaviors after aversive stimuli is activated by ...
Juan Xin, Weiran Shan, Jun Li, Hai Yu, Zhiyi Zuo   +4 more
semanticscholar   +1 more source

Impaired synaptic plasticity and decreased glutamatergic neuron excitability induced by SIRT1/BDNF downregulation in the hippocampal CA1 region are involved in postoperative cognitive dysfunction

Cellular & Molecular Biology Letters
Background Postoperative cognitive dysfunction (POCD) is a common complication after anesthesia/surgery, especially among elderly patients, and poses a significant threat to their postoperative quality of life and overall well-being.
Wei-Feng Wu, Chen Chen, Jiatao Lin, X. Jiao, Wei Dong, Jie Wan, Qiang Liu, Yonghong Qiu, Ao Sun, Yi-Qi Liu, Chun-Hui Jin, He Huang, Hui Zheng, Cheng-hua Zhou, Yu-Qing Wu   +14 more
semanticscholar   +1 more source

Update on the Mechanism and Treatment of Sevoflurane-Induced Postoperative Cognitive Dysfunction

Frontiers in Aging Neuroscience, 2021
Sevoflurane is one of the most widely used anesthetics for the induction and maintenance of general anesthesia in surgical patients. Sevoflurane treatment may increase the incidence of postoperative cognitive dysfunction (POCD), and patients with POCD ...
Cong Wang, Wei-can Chen, Yan Zhang, Shu Lin, He-fan He   +4 more
semanticscholar   +1 more source

Postoperative Delirium and Postoperative Cognitive Dysfunction in Patients with Elective Hip or Knee Arthroplasty: A Narrative Review of the Literature

Life, 2022
Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications following total knee arthroplasty (TKA) and total hip arthroplasty (THA), affecting the length of hospital stay and increasing medical complications ...
Petros Kitsis, Theopisti Zisimou, I. Gkiatas, Ioannis P. Kostas-Agnantis, I. Gelalis, A. Korompilias, E. Pakos   +6 more
semanticscholar   +1 more source