Results 111 to 120 of about 21,696 (208)

Targeted Prophylaxis of Postoperative Delirium [PDF]

Anesthesiology, 2012
Saager, Leif, Sessler, Daniel I.
openaire   +3 more sources

Pre‐Fracture Cognitive Assessment Using the DASC‐21 and Postoperative Delirium Risk

Psychogeriatrics, Volume 26, Issue 5, September 2026.
ABSTRACT Background Postoperative delirium (POD) is a common complication in older adults after hip fracture surgery. Although cognitive impairment is a key risk factor, accurately assessing baseline cognition in acute settings remains challenging.
Tomoko Kamimura, Satoshi Tamaki, Yuya Kobayashi, Keita Tomii   +3 more
wiley   +1 more source

Reducing postoperative delirium [PDF]

Anaesthesia, 2014
openaire   +2 more sources

Progression to Dementia in Very Late‐Onset Schizophrenia‐Like Psychosis Stratified by Alzheimer's Disease and Lewy Body Disease Biomarkers: A Retrospective Cohort Study

Psychogeriatrics, Volume 26, Issue 5, September 2026.
ABSTRACT Background Very late‐onset schizophrenia‐like psychosis (VLOSLP) is clinically heterogeneous, and its relationship with dementia‐related neurodegenerative disease remains unresolved. We examined whether Alzheimer's disease (AD) and Lewy body disease (LBD) biomarker status were associated with dementia progression in VLOSLP.
Yuto Satake, Hideki Kanemoto, Daiki Taomoto, Kayo Takeda, Shigeki Katakami, Matasaburo Kobayashi, Keiko Matsunaga, Kayako Isohashi, Takashi Suehiro, Kenji Yoshiyama, Manabu Ikeda   +10 more
wiley   +1 more source

hUC‐MSCs via β‐NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2‐SARM1‐NF‐κB Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study found that human umbilical cord mesenchymal stem cells secrete β‐NGF, which binds to the TrkA receptor on neurons, upregulates the protein levels of STMN2 and NMNAT2 in mice with perioperative neurocognitive disorders, and thereby downregulates the protein levels of SARM1 and p‐NF‐κB.
Kai Wang, Fangjun Wang, Yuhan Zhang, Wenbo Li, Shuai Li, Ying Zhou, Guangkuo Ma, Ziwei Xia, Xueyan Zhou, Liwei Wang   +9 more
wiley   +1 more source

Sarcopenia Predicts Postoperative Cognitive Impairment and Poor Surgical Outcomes in Older Adults: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Sarcopenia is a progressive skeletal muscle disorder prevalent in older adults, yet its role as a risk factor for acute postoperative cognitive decline—an early manifestation within the spectrum of perioperative neurocognitive disorders (PND)—remains underexplored.
Xingming Tang, Yuncai Gu, Li Wang, Xiaochu Wu, Yipu Ren, Shudie Zhou, Yulong Cai, Xian Du, Xun Xia, Tianyao Zhang   +9 more
wiley   +1 more source

Tracheostomy vs. Delayed Extubation in Head and Neck Reconstruction: A Meta‐Analysis

The Laryngoscope, Volume 136, Issue 8, Page 3325-3334, August 2026.
High volume centers are trialing delayed extubation as an alternative management approach to tracheostomy in patients undergoing head and neck reconstruction (HNR). This systematic review shows that patients in the delayed extubation group are four times less likely to suffer an airway complication (p = 0.295) and eight times less likely to suffer a ...
Sahil Goel, Christine Lee, Ken Lin, Lee Pryor, Guy Ludbrook, Andrew Foreman, John‐Charles Hodge   +6 more
wiley   +1 more source

Inhibiting the Endothelial Mechanosensitive Channel Piezo1 Restores Hippocampal Blood–Brain Barrier Integrity to Improve Anesthesia‐ and Surgery‐Induced Cognitive Decline

MedComm, Volume 7, Issue 8, August 2026.
Approximately 10%–30% of elderly patients develop cognitive decline after surgery. How brain regions coordinate cellular networks to mediate this remains unclear. Anesthesia/surgery induces Piezo1 in hippocampal endothelial cells of aged mice. Endothelial Piezo1 deletion restores BBB integrity and improves cognition.
Yong Qiu, Chunheng Mo, Jinyan Wu, Jiachen Li, Shiyu Xu, Lu Chen, Liyin Zhang, Xingming Huang, Yi Zhang, Meng Sun, Yi Kang, Tao Zhu, Bi‐Sen Ding, Guo Chen   +13 more
wiley   +1 more source

A Review of the Role of Ketamine in the Management of Delirium Following Coronary Artery Bypass Graft Surgery and its impact on Timing of Patient Extubation [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Delirium is a disruption of consciousness and cognitive function that frequently occurs in the postoperative period. The incidence of delirium following open-heart surgery has been reported to exceed 90%, potentially leading to ...
Maryam Aligholizadeh, Mehrdad Mesbah Kiaei, Siavash Sangi, Melika Aligholizadeh, Homayoon Bana Derakhshan, Zahra Karimian   +5 more
doaj  

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, Volume 36, Issue 8, Page 887-898, August 2026.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source