Results 121 to 130 of about 434,406 (341)

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Gastric tube ulcer perforating the pericardium after subtotal esophagectomy [Perforacija ulkusa želučanog supstituta u perikard nakon subtotalne ezofagektomije] [PDF]

, 2013
Subtotal esophagectomy with retrosternal transposition of the gastric tube to the neck was performed in a 62-year-old patient with squamous cell carcinoma of the proximal third of the esophagus.
Korušić, Anđelko, Mikecin, Verica, Nikolić, Igor, Stančić-Rokotov, Dinko, Đuzel, Viktor, Špiček Macan, Jasna   +5 more
core  

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

Advanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen, Qing Zhao, Wentao Fu, Weixian Chen, Xiaoqian Zhang, Gaiying Ye, Qinglei Meng, Liyuan Shao, Qian Ma, Lin Zhao, Ying Zhao, Weihua Guo   +11 more
wiley   +1 more source

Nomogram for predicting postoperative pulmonary infection in elderly patients undergoing major orthopedic surgery

Frontiers in Medicine
ObjectiveThe incidence of pulmonary infection following major orthopedic surgery in the elderly is high, significantly affecting prognosis. Identifying high-risk factors and stratifying patient risk more effectively is an urgent problem that needs to be ...
Yuhan Liu, Yunping Fan, Xuping Yang, Haibin Gan, Xiaohua Li, Yanrong Luo, Qianyun Pang, Tingjun Yang   +7 more
doaj   +1 more source

Classification of postoperative surgical site infections from blood measurements with missing data using recurrent neural networks

, 2017
Clinical measurements that can be represented as time series constitute an important fraction of the electronic health records and are often both uncertain and incomplete.
Bianchi, Filippo Maria, Jenssen, Robert, Kampffmeyer, Michael, Mikalsen, Karl Øyvind, Soguero-Ruiz, Cristina, Strauman, Andreas Storvik   +5 more
core   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Minimally invasive management of deep incisional infection following posterior spinal surgery: a case report

Frontiers in Medicine
BackgroundIn recent years, innovations in spinal surgical techniques have significantly improved clinical outcomes and quality of life for patients with spinal diseases.
Hongbin Wang, Jing Xu, Lanlan Pang, Luyue Bai, Xutao Fan   +4 more
doaj   +1 more source

Wound conditioning by vacuum assisted closure (V.A.C.) in postoperative infections after dorsal spine surgery [PDF]

, 2006
Ludwig Labler, Marius Keel, O. Trentz, Michael Heinzelmann   +3 more
openalex   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source