Results 141 to 150 of about 3,015,811 (400)

Biodegradable Medical Implants: Reshaping Future Medical Practice

open access: yesAdvanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia   +4 more
wiley   +1 more source

Postoperative pain management in the postanesthesia care unit: an update

open access: yesJournal of Pain Research, 2017
Acute postoperative pain remains a major problem, resulting in multiple undesirable outcomes if inadequately controlled. Most surgical patients spend their immediate postoperative period in the postanesthesia care unit (PACU), where pain management ...
Jie Luo, S. Min
semanticscholar   +1 more source

Bioactive siRNA‐Based Liposomes Promoted Tendon‐Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248+ TSPCs

open access: yesAdvanced Science, EarlyView.
In this study, it is found that osteoporosis leads to disturbances in the Extracellular Matrix (ECM)of tendons and thus causes a decrease in TSPC stemness, resulting in a rotator cuff that is easily damaged and prone to retearing after repair. Targeted intervention with si‐CD248‐loaded liposomes can restore TSPC stemness, promote tendon‐bone healing ...
Yinhua Qian   +14 more
wiley   +1 more source

Mechanically Active Hydrogel for Healing Intestinal Fistulas through the YAP‐Mediated Mechanosensitization of Intestinal Epithelial Cells

open access: yesAdvanced Science, EarlyView.
This study develops the hydrogel with antimicrobial, adhesive, degradable, injectable, and temperature‐sensitive contraction properties based on the transcriptomic and pathological characteristics of intestinal fistula patients. This hydrogel can seal rabbit intestinal fistula in situ, reduce the intestinal defect, and promote intestinal epithelial ...
Ze Li   +12 more
wiley   +1 more source

Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]

open access: yes, 2018
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J.   +2 more
core   +1 more source

Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis

open access: yesAdvanced Science, EarlyView.
In this study, it is discovered that pathological accumulation of Runx2+ Schwann cell clusters​ during axonal regeneration is a key factor impairing nerve repair in aging. This pathology is associated with ​dysregulation of stress granule homeostasis.
Peilin Wang   +10 more
wiley   +1 more source

Effects of Lidocaine on Reducing the Need for Anesthetic Drugs during Ophthalmologic Surgeries

open access: yesمجله دانشکده پزشکی اصفهان, 2013
Background: The most common postoperative complications are pain, vomiting, and nausea. They may in turn lead to other complications such as wound damage. On the other hand, the use of opioid analgesics has unwanted effects on patients.
Hassan Ali Soltani   +2 more
doaj  

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang   +15 more
wiley   +1 more source

An Injectable Zwitterionic Hydrogels with Multiple Intermolecular Interactions for Effective Prevention of Abdominal Adhesions

open access: yesAdvanced Science, EarlyView.
An injectable PSA‐ZnO through multiple intermolecular including hydrogen bonds and electrostatic interactions for effectively prevents abdominal adhesions. The PSA‐ZnO hydrogel demonstrates superior wound healing promotion (≥ 95%) and more effective inhibition of scar formation compared to the commercial 3M dressing (≈80%), and prevents post‐operative ...
Na Wen   +9 more
wiley   +1 more source

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