Results 81 to 90 of about 3,204,314 (308)
A Mouse Model of Postoperative Pain
Postoperative pain is highly debilitating and hinders recovery. Opioids are the main pain medication used for acute postoperative pain. Given the devastating opioid addiction and overdose epidemic across the US, non-opioid pain therapeutics are ...
Ashley Cowie, Cheryl Stucky
doaj +1 more source
H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou +12 more
wiley +1 more source
Background Spontaneous intracerebral hemorrhage (ICH) accounts for 9–27% of all strokes worldwide and is associated with high mortality and disability. The main causes include vascular malformations, small- and large-vessel angiopathies, and coagulation ...
Gianluigi Morello +30 more
doaj +1 more source
Background: Tonsillectomy is a common procedure often associated with severe postoperative pain. This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compared with fentanyl.
Michael Bøndergaard +8 more
doaj +1 more source
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Chronic postoperative pain: recent findings in understanding and management
Chronic postoperative pain is a poorly recognized potential outcome from surgery. It affects millions of patients every year, with pain lasting for months to years, resulting in patient suffering and ensuing economic consequences. The operations with the
D. Correll
semanticscholar +1 more source
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley +1 more source
Caregivers’ role regarding managing postoperative pain of hospitalised children (0–3 years)
Background: Acute postoperative pain is a common surgical symptom affecting 40% - 80% of patients. Postoperative pain produces much distress in children. Effective postoperative pain management is a human right. Various stakeholders, including caregivers,
Sylvia Oger Ofosu-Dwamena +3 more
doaj +1 more source

