Results 191 to 200 of about 1,818 (256)

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

open access: yesArchaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith   +5 more
wiley   +1 more source

Health Insurance Coverage and Rural–Urban Differences in Maternal Health Care Among Postpartum Women—National Health Interview Survey

open access: yesBirth, EarlyView.
Are there rural–urban differences in maternal health and care among postpartum women, and do those differences vary by insurance coverage? This study used the 2013–2018 National Health Interview Surveys of 2,664 non‐pregnant female respondents ages 18–49 with an infant under age one.
Julia D. Interrante   +4 more
wiley   +1 more source

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang   +11 more
wiley   +1 more source

Potentiation effects of the positive allosteric modulator PTC‐174 on NMDA receptors in neonatal male rat substantia nigra dopaminergic neurons

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Positive allosteric modulators bind to secondary binding sites on the receptor and alter receptor conformation and activation, changing agonist potency and efficacy. PTC‐174 is a novel NMDA receptor positive allosteric modulator that particularly enhances activity of receptors containing GluN2C or GluN2D subunits.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

Perinatal Mood Disorders in Polish Women: A Cross-Sectional Study. [PDF]

open access: yesJ Clin Med
Mróz M   +6 more
europepmc   +1 more source

NMDA receptor subunit‐dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Radiprodil is a GluN2B subunit selective NMDA receptor negative allosteric modulator which is currently under clinical investigation as a possible anti‐epileptic drug for paediatric use. Our goal was to investigate the inhibition of dopaminergic neuron NMDA responses by radiprodil.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

open access: yesCell Proliferation, EarlyView.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin   +7 more
wiley   +1 more source

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