Results 91 to 100 of about 113,546 (307)
Parity Early Stage of Marriage with Incidence of Postpartum Depression [PDF]
, 2014 Postpartum depression is a condition that may be experienced by women. If it is not addressed properly, it will have a negative impact. Determine the correlation between parity and the early stage of the marriage with the incidence of postpartum ...
Ambarwati, E. R. (Eny) +1 more
core +2 more sources
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Arthritis &Rheumatology, EarlyView.Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Frontiers in PsychiatryBackgroundFew studies have compared the influencing factors of postpartum depression between primiparous and multiparous women. Therefore, this study is aimed to investigate the prevalence and influencing factors of postpartum depression in primiparous ...
Jing Zhang +4 more
doaj +1 more source
ROLE OF OMEGA-3 FATTY ACIDS ON POSTPARTUM DEPRESSION [PDF]
Introduction: Women in child-bearing age are at risk of postpartum depression. Several drugs have been introduced for treatment, but because of their side effects and also breast feeding women's desire for dietary complements rather than chemical drugs ...
ایوان بقاء, ریحانه +3 more
core
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Postnatal depression and reproductive success in modern, low-fertility contexts [PDF]
, 2015 Background and objectives: Postnatal depression (PND) presents a puzzling phenomenon to evolutionary anthropologists as it is highly prevalent and yet detrimental to child development and maternal health.
Burger, Oskar F. +2 more
core +2 more sources
Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders
Bulletin of the Korean Chemical Society, EarlyView.5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley +1 more source
Circulating JKAP levels may correlate with postpartum anxiety and depression through its interaction with T helper 17 cells [PDF]
Brazilian Journal of Medical and Biological ResearchJun N-terminal kinase pathway-associated phosphatase (JKAP) regulates CD4+ T-cell differentiation and immunity, which are linked to mental disorders. This study aimed to explore the relationships between JKAP and T helper 17 (Th17)/regulatory T (Treg ...
Jing Zhang +6 more
doaj +1 more source