Results 111 to 120 of about 45,056 (263)

Codeine and Metabolite Concentrations in the Breastfed Neonate

Pediatric Anesthesia, EarlyView.
ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley   +1 more source

Prenatal Magnetic Resonance Imaging Assessment of Fetal Airway Dimensions: Establishing an Anthropometric Database

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Fetal airway anomalies can severely impair breathing at birth, potentially causing brain injury or death. Thus, early prenatal diagnosis is essential. While MRI is the most effective imaging modality for evaluating fetal airways, normative MRI data remain scarce.
Juliette Houssin, Ahmed El Ahmadi, Robinson Gravier‐Dumonceau, Richard Nicollas, Eric Moreddu   +4 more
wiley   +1 more source

Prenatal Spectrum of COL2A1‐Related Spondyloepiphyseal Dysplasia Congenita: A Review and Two Case Reports

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To review the published literature on prenatal findings of COL2A1‐related SEDC, summarizing reported imaging and molecular variants, and to describe two additional prenatal cases evaluated at a tertiary referral center. Method A narrative review with a systematic search strategy was conducted to analyze prenatal imaging findings ...
López‐Rodríguez Larissa, León‐Madero Luis Felipe, Jiménez‐Chaidez Salvador, Gallardo‐Gaona Juan Manuel, Rodríguez‐Sibaja María Jose, Castañeda‐de‐la‐Fuente Angelica, Del Castillo‐Reyes Katia Alejandra, Yañez‐Felix Ana Lucia, Morales‐Dominguez Valeria, Borboa‐Olivares Héctor Jesús, Sevilla‐Montoya Rosalba   +10 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

“For three of my four miscarriages I was at work…” Experiences of miscarriage, infertility and assisted fertility in veterinary workplaces

Veterinary Record, EarlyView.
Abstract Background Miscarriage, infertility and assisted fertility (MIAF) can profoundly impact physical and mental health. The aims of this study were to investigate how veterinary professionals’ work environments and employers impacted their experiences of MIAF and to identify how workplace experiences of MIAF could be improved.
Jenny Stavisky, Natalie Scroggie, Abi Collinson, Zoe Belshaw   +3 more
wiley   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source

The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot, B. Schotsman, E. Oostra, A. W. Hoogendoorn, B. W. C. Storosum, C. H. M. Planting, H. M. Heller, J. J. B. van der Vlugt, J. G. van Mill, L. J. C. A. Smarius, M. S. Oudijn, M. S. van Noorden, S. M. M. Lange, Y. D. van der Werf, E. van Exel   +14 more
wiley   +1 more source

Psychiatric History and Postpartum Depression: The Mediating Role of Obstetric Complications

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Psychiatric history is the strongest risk factor for postpartum depression (PPD). Obstetric complications, more prevalent among women with a psychiatric history, are also independent risk factors. However, the mechanisms linking these factors to PPD remain unclear.
Mette‐Marie Zacher Kjeldsen, Katrine Holde, Line Bager, Veerle Bergink, Emely Ek Blæhr, Janne Tidselbak Larsen, Kathrine Bang Madsen, Merete Lund Mægbæk, Liselotte Vogdrup Petersen, Trine Munk‐Olsen   +9 more
wiley   +1 more source

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

Anaesthesia, EarlyView.
Summary Introduction Labour epidural analgesia is the most effective method for intrapartum pain relief and is associated with improved maternal outcomes. However, concerns have been raised regarding potential associations between labour epidural analgesia and adverse psycho‐emotional outcomes in children. Evidence from large epidemiological studies is
Sana Asif, Hsing‐Fen Tu, Richard A. White, Birgitta Birgisdottir, Miklos Lipcsey, Martin F. Bjurström, Alkistis Skalkidou   +6 more
wiley   +1 more source

Paternal Postpartum Depression in South Asia. [PDF]

Public Health Chall
Yasir Arafat SM, Hossain S.
europepmc   +1 more source