Results 51 to 60 of about 37,978 (301)

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Postpartum depression and its association with social support: a cross sectional study at a maternity hospital in Kerala.

Kerala Journal of Psychiatry, 2020
Background: Childbirth is associated with significant physiological changes as well as challenges related to psychiatric disorders. Postpartum depression (PPD) is one such condition associated with high levels of morbidity and mortality.
Kuriakose Santhosh , S Vinaychandran, K T P Dayal Narayan, C H Mini   +3 more
doaj   +3 more sources

The Blurred Line between Physical Ageing and Mental Health in Older Adults: Implications for the Measurement of Depression [PDF]

, 2019
Objectives: Depression in older adults is assessed using measures validated in the general adult population. However, such measures may be inappropriate in the elderly due to the similarities between ageing and the symptoms of depression.
Hazell, C., Hazell, C., Jones, C., Jones, C., Smith, Helen E, Smith, Helen E   +5 more
core   +1 more source

Screening postpartum depression with the Taiwanese version of the Edinburgh Postnatal Depression Scale

Comprehensive Psychiatry, 2005
This study is intended to develop the Taiwanese version of the Edinburgh Postnatal Depression Scale (EPDS-T), to evaluate its validity, and to estimate the prevalence of postpartum depressive disorders (PPD) among Taiwanese women. A prospective cohort of 203 subjects who completed the EPDS-T, the Beck Depression Inventory (BDI-II), and postpartum ...
Hui-Wen, Teng, Chun-Sen, Hsu, Shou-Mei, Shih, Mong-Liang, Lu, Jan-Jhy, Pan, Winston W, Shen   +5 more
openaire   +2 more sources

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Screening for individuals with postpartum depression by an attenuated and delayed niacin skin flushing response: a case control study

BMC Pregnancy and Childbirth
Background Postpartum depression (PPD) affects maternal mental health extensively and is challenged by the lack of objective diagnostic methods. This study aimed to explore the characteristics of niacin skin flush response, a diagnostic marker for ...
Dandan Wang, Yan Gao, Zhendong Xu, Fuyi Shen, Xiaowen Hu, Xuhan Yang, Qian Wang, Juan Zhang, Jie Jiang, Yan Zhuang, Lize Xiong, Jun Li, Chunling Wan, Zhiqiang Liu   +13 more
doaj   +1 more source

Depressive symptoms in postpartum women at Family Health Units

Revista Brasileira de Saúde Materno Infantil
Objectives: to identify postpartum depression among women assisted by Family Health Units (FHU). Methods: this is a cross-sectional study with a quantitative approach carried out in FHUs at the city of Vitoria de Santo Antão - PE.
Synara Barbosa de Melo, Rhayza Rhavênia Rodrigues Jordão, Fernanda Jorge Guimarães, Jaqueline Galdino Albuquerque Perrelli, Amaury Cantilino, Everton Botelho Sougey   +5 more
doaj   +1 more source

Validation of the World Health Organization-5 well-being index; assessment of maternal well-being and its associated factors [PDF]

, 2015
Objective: The aim of this study was to validate the World Health Organization-5 Well-Being Index (WHO-5) in a sample of pregnant Iranian women, to explore the changes in maternal well-being from pregnancy to postpartum, and to determine the factors ...
Chaman, R., Khosravi, A., Mortazavi, F., Mousavi, S.-A.   +3 more
core  

Perinatal depression and patterns of attachment: a critical risk factor? [PDF]

, 2015
Background. This study aims to verify if the presence and severity of perinatal depression are related to any particular pattern of attachment. Methods.
Aceti, Franca, Biondi, Massimo, Carluccio, GIUSEPPE MATTIA, Ciolli, Paola, Giacchetti, Nicoletta, Giancola, Orazio, Marini, Isabella, Meuti, Valentina, Zaccagni, Michela   +8 more
core   +4 more sources

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source