Results 51 to 60 of about 565 (205)

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Postpartum depression: Prevention and multimodal therapy

Journal of Mind and Medical Sciences, 2018
A woman goes through many biological (hormonal, physical), psychological (emotional), and socio-cultural changes during pregnancy. Furthermore, changes also occur in the mother's familial and interpersonal world after childbirth.
Anca Daniela Stanescu, Denisa Oana Balalau, Liana Ples, Stana Paunica, Cristian Balalau   +4 more
doaj   +1 more source

Postpartum Depression and its Associated Factors among Postpartum Mothers Attending a Teaching Hospital in Eastern Nepal

Journal of Nobel Medical College, 2020
Background: Postnatal depression is an important and burning public health issue in modern civilization with the strongest connection to adverse outcome for children and also maternal morbidity.
Pratikshya Tripathi, Ganesh Devkota, Prithi Bahadur Rai   +2 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Did the French pregnancy pictogram change antiseizure medication use during pregnancy?

Epilepsia, EarlyView.
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo, Christine Damase‐Michel, Marie Denuelle, Sébastien Boulogne, Laurane Delteil, Monica Saucedo, Catherine Deneux‐Tharaux, Isabelle Lacroix   +7 more
wiley   +1 more source

Associations between domestic violence and psychosomatic symptoms and health behaviors during pregnancy and the puerperium: a comparative cross-sectional study

Frontiers in Global Women's Health
BackgroundAccording to the WHO, violence is the intentional use of force or power against oneself, another person, or a community, causing injury, death, or harm.
Ana Bertha Zavalza-Gómez, Andrea Meza-Martínez, Sergio Jiram Vázquez-Sánchez, Evelin Castillo-Martínez, Samantha Emily González-Muñoz, Andrea García, Kathia Dayana Morfín Meza, Alejandro González-Ojeda, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Sol Ramírez-Ochoa, Andrea Socorro Álvarez-Villaseñor, Ana Olivia Cortés-Flores, Guadalupe Castillo Cardiel, Clotilde Fuentes-Orozco, Ramirez Velazquez Alejandro   +15 more
doaj   +1 more source

The role of intimate partner violence victimization during pregnancy on maternal postpartum depression in Eastern Ethiopia

SAGE Open Medicine, 2021
Background: Intimate partner violence during pregnancy is a strong predictor of maternal postpartum depression. In Ethiopia, evidence on the association of intimate partner violence during pregnancy with postpartum depression is very limited.
Wondimye Ashenafi, Bezatu Mengistie, Gudina Egata, Yemane Berhane   +3 more
doaj   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source