Results 241 to 250 of about 282,002 (386)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

When Is Postpartum Haemorrhage Treatment Initiated? A Nested Observational Study Within the E-MOTIVE Trial. [PDF]

BJOG
Mammoliti KM, Althabe F, Easter C, Devall A, Martin J, Funmi AL, Yusuf R, Abubakar F, Arigbede LC, Mugambi J, Oyoo P, Sambusa M, Banda A, Samuels F, Willemse S, Khambule SD, Shu'aib HM, Wakili AA, Okore J, Mwampashi A, Singata-Madliki M, Arends E, Muller E, Galadanci H, Qureshi Z, Al-Beity FA, Hofmeyr GJ, Fawcus S, Moran N, Gwako G, Osoti A, Gallos I, Coomarasamy A.   +32 more
europepmc   +1 more source

Postpartum haemorrhage

Biomedical Imaging and Intervention Journal, 2005
S.I. Mohamed, B.J.J. Abdullah, S.Z. Omar
openaire   +1 more source

Updating of a clinical protocol for the prevention and management of postpartum haemorrhage at Kenyatta National Hospital, Nairobi, Kenya

, 2018
Anne Pulei, N.A. Shatry, Matt Sura, Martin Njoroge, Davies K. Kibii, D.K. Mwaniki, H.P. Teko, O. Maranga, Omondi Ogutu, Joshua P. Vogel, Zaid Qureshi   +10 more
openalex   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Severe postpartum haemorrhage at a large referral hospital in Uganda: A prospective observational pilot study. [PDF]

PLoS One
Appelbäck M, Lubulwa C, Kazibwe L, Stensæth KH, Tylleskär T, Byamugisha J.   +5 more
europepmc   +1 more source

Prenatal anaemia and risk of postpartum haemorrhage: a cohort analysis of data from the Predict-PPH study [PDF]

Kehinde S. Okunade, Adebola A. Adejimi, Ayokunle Moses Olumodeji, Atinuke Olowe, Olufemi Abiola Oyedeji, Iyabo Y. Ademuyiwa, Hameed Adelabu, Eselobu Toks-Omage, Austin C. Okoro, Nosimot Omolola Davies, M. A Adenekan, Temitope Olumuyiwa Ojo, Kabiru Afolarin Rabiu, Yusuf A. Oshodi, Aloy Okechukwu Ugwu, Festus Olusola Olowoselu, Olukayode O. Akinmola, J A Olamijulo, Ayodeji A. Oluwole   +18 more
openalex   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Effects of combinations of diagnostic and treatment strategies for postpartum haemorrhage: a network meta-analysis. [PDF]

Cochrane Database Syst Rev
Yunas I, Price MJ, Vigneswaran K, Tobias A, Devall AJ, Coomarasamy A.   +5 more
europepmc   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source