Results 41 to 50 of about 53,778 (297)

Clinical Management of Postpartum Hemorrhage in Community Birthing Hospitals in Vermont: A Gap Analysis to Promote Best Practice [PDF]

, 2020
Purpose: Despite advances in research and medical technology, the rates of postpartum hemorrhage (PPH) continue to rise. Annually, these preventable events are the cause of one-fourth of maternal deaths worldwide.
Greene, Rachel
core   +1 more source

Emergent management of postpartum hemorrhage for the general and acute care surgeon [PDF]

, 2009
Background Postpartum hemorrhage is one of the rare occasions when a general or acute care surgeon may be emergently called to labor and delivery, a situation in which time is limited and the stakes high.
Allison B Weisbrod, Forest R Sheppard, Mildred R Chernofsky, Charles L Blankenship, Frederick Gage, Gary Wind, Eric A Elster, William A Liston   +7 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

The association between maternal vitamin D deficiency and postpartum hemorrhage and uterine atony

Acta Obstetricia et Gynecologica Scandinavica
Introduction Postpartum hemorrhage is the leading cause of maternal morbidity and mortality worldwide. There are several known risk factors for postpartum hemorrhage related to pregnancy and delivery, but less evidence of predisposing factors.
Anna Sörsjö Stevenazzi, Sofia Pihl, Marie Blomberg, Daniel Axelsson   +3 more
doaj   +1 more source

Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States [PDF]

, 2014
Objective: To determine whether use of serotonin or non-serotonin reuptake inhibitors near to delivery is associated with postpartum hemorrhage. Design Cohort study. Setting 2000-07 nationwide Medicaid data (Medicaid Analytic eXtract). Population 106 000
Achtyes, Eric D, Hernández-Díaz, Sonia, Huybrechts, Krista F, Michels, Karin B, Mogun, Helen, Palmsten, Kristin, Setoguchi, Soko, Williams, Paige L   +7 more
core   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Bidirectional Psychoneuroimmune Interactions in the Early Postpartum Period Influence Risk of Postpartum Depression [PDF]

, 2015
More than 500,000 U.S. women develop postpartum depression (PPD) annually. Although psychosocial risks are known, the underlying biology remains unclear.
Aagaard-Tillery, Albacar, Anderson, Anisman, Association, Beck, Bensimon, Besedovsky, Besedovsky, Binder, Bloch, Bloch, Boufidou, Chapwanya, Charmandari, Chaudron, Christiaens, Christian, Chrousos, Chrousos, Cohen, Corwin, Corwin, Corwin, Corwin, Costas, Cox, Dantzer, Dennis, Donna O. McCarthy, Elenkov, Elenkov, Elizabeth J. Corwin, Field, Figueira, Fredericks, Gavin, Glynn, Goshtasebi, Groer, Guilbaud, Guintivano, Hay, Hebisch, Hojilla, Kalantaridou, Kathleen Pajer, Kimmel, Le Donne, Maes, Maes, Mary Weber, Mastorakos, Miller, Miller, Miller, Miller, Mor, Nancy Lowe, Nilsen-Hamilton, Okun, Osborne, O’Keane, Pace, Pace, Pearson, Petrovsky, Petrovsky, Pruessner, Raison, Raison, Ruiz, Salamonsen, Shelton, Steptoe, Sudeshna Paul, Taraz, Teissedre, Tsigos, Vitoratos, Watkins, Wisner, Yang, Yim   +83 more
core   +2 more sources

Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review [PDF]

, 2020
According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies ...
Andronache, Liliana Florina, Bohiltea, Roxana, Cavinder, Christina M., Cirstoiu, Monica Mihaela, Ducu, Ionită, Paunica, Ioana, Turcan, Natalia   +6 more
core   +2 more sources

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source