Results 51 to 60 of about 34,638 (301)

Duration of labor and the risk of severe postpartum hemorrhage: A case-control study.

PLoS ONE, 2017
ObjectiveOur main objective was to investigate the association between duration of active labor and severe postpartum hemorrhage. We examined the effect of the total duration of active labor, the effect of each stage of active labor, and the gradient ...
Lill Trine Nyfløt, Babill Stray-Pedersen, Lisa Forsén, Siri Vangen   +3 more
doaj   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Prenatal Plasma Fibrinogen Level Predicts Postpartum Hemorrhage of Patients With HELLP Syndrome

Clinical and Applied Thrombosis/Hemostasis, 2020
H emolysis, e levated l iver enzymes, and l ow p latelets (HELLP) syndrome is a serious complication of pregnancy. Postpartum hemorrhage indicates poor prognosis of pregnant women with HELLP syndrome. The aim of our study is to investigate the predictive
Chanjuan Cui, Sisi Ma, Rui Qiao
doaj   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

POSTPARTUM HEMORRHAGE RECOGNITION AND TREATMENT

, 2021
The purpose of this thesis is to explore how postpartum interventions impact the rate of maternal mortality and morbidity caused by postpartum hemorrhage and to provide evidenced based recommendations for postpartum hemorrhage interventions.
Blawn, Kamryn Danielle
core  

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source

Proportions of severe postpartum hemorrhage (>1500ml) within type specific postpartum hemorrhage (1999–2017); singleton births, ≥22 weeks of gestation.

, 2022
Proportions of severe postpartum hemorrhage (>1500ml) within type specific postpartum hemorrhage (1999–2017); singleton births, ≥22 weeks of gestation.
Svein Rasmussen (439706), Lorentz Erland Linde (5018819), Dag Moster (3122211), Jörg Kessler (168524), Elham Baghestan (8292753), Mika Gissler (283684), Cathrine Ebbing (439703)   +6 more
core   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Peripartum hysterectomy due to severe postpartum hemorrhage: A hospital‐based study

Acta Obstetricia et Gynecologica Scandinavica, 2022
Introduction A peripartum hysterectomy is typically performed as a lifesaving procedure in obstetrics to manage severe postpartum hemorrhage. Severe hemorrhages that lead to peripartum hysterectomies are mainly caused by uterine atony and placenta ...
Silje Pettersen, Ragnhild Sørum Falk, Siri Vangen, Lill T. Nyfløt   +3 more
doaj   +1 more source