Results 51 to 60 of about 585,226 (323)

Prophylactic tranexamic acid for reducing intraoperative blood loss during cesarean section in women at high risk of postpartum hemorrhage: A double-blind placebo randomized controlled trial

Women's Health
Background: Postpartum hemorrhage remains a leading cause of maternal mortality especially in developing countries. The majority of previous trials on the effectiveness of tranexamic acid in reducing blood loss were performed in low-risk women for ...
Kelvin E. Ortuanya, G. Eleje, F. O. Ezugwu, B. Odugu, J. Ikechebelu, E. Ugwu, A. Eke, Fredrick I Awkadigwe, M. N. Ezenwaeze, I. Ofor, C. C. Okafor, C. G. Okafor   +11 more
semanticscholar   +1 more source

Inferior Mesenteric Artery Embolization with N-Butyl Cyanoacrylate for Life-Threatening Postpartum Hemorrhage: A Report of Two Cases and Literature Review

대한영상의학회지, 2021
The inferior mesenteric artery is a rare source of postpartum hemorrhage. We report two cases of primary postpartum hemorrhage that originated from the inferior mesenteric artery after vaginal delivery.
Hae Won Yoo, Min Jeong Choi, Bong Man Kim   +2 more
doaj   +1 more source

Association of Gestational Age with Postpartum Hemorrhage: An International Cohort Study

Anesthesiology, 2021
Background: Risk factors for postpartum hemorrhage, such as chorioamnionitis and multiple gestation, have been identified in previous epidemiologic studies.
A. Butwick, Can Liu, N. Guo, J. Bentley, E. Main, J. Mayo, G. Shaw, O. Stephansson   +7 more
semanticscholar   +1 more source

UTERINE COMPRESSION SUTURES: A METHOD OF SURGICAL HAEMOSTASIS DURING CAESAREAN DELIVERY (HYSTEROSCOPIC ASSESSMENT)

В мире научных открытий, 2017
Background: to assess the efficiency of uterine compression sutures in treatment of severe postpartum hemorrhage. Materials and methods: 55 patients who had been performed cesarean section from 2013 to 2015 were examined.
Maria Petrovna Evseeva, Aleksandr Nikolaevich Ivanyan, Larisa Simonovna Kirakosyan   +2 more
doaj   +1 more source

Disastrous delayed postpartum hemorrhage after 3 days of Shenghua decoction treatment

Tzu Chi Medical Journal, 2020
Taiwanese women frequently receive Shenghua decoction treatment for uterus involution. However, prolonged Shenghua decoction treatment can be detrimental.
Hui-Hua Chen, Yueh-Hung Chou, Ho-Hsiung Lin, Sheng-Mou Hsiao   +3 more
doaj   +1 more source

Viscoelastic Hemostatic Assays for Postpartum Hemorrhage

Journal of Clinical Medicine, 2021
This article discusses the importance and effectiveness of viscoelastic hemostatic assays (VHAs) in assessing hemostatic competence and guiding blood component therapy (BCT) in patients with postpartum hemorrhage (PPH).
A. Liew-Spilger, Nikki R Sorg, Toby J Brenner, J. Langford, Margaret Berquist, Natalie M Mark, Spencer H Moore, J. Mark, S. Baumgartner, M. Abernathy   +9 more
semanticscholar   +1 more source

Retained placenta and postpartum hemorrhage: time is not everything

Archives of Gynecology and Obstetrics, 2021
Postpartum hemorrhage is the major cause of maternal mortality worldwide. Retained placenta accounts for nearly 20% of severe cases. We investigated the influence of the time factor and retained placenta etiology on postpartum hemorrhage dynamics.
D. Franke, J. Zepf, T. Burkhardt, P. Stein, R. Zimmermann, C. Haslinger   +5 more
semanticscholar   +1 more source

Evaluating Tranexamic Acid Dosing Strategies for Postpartum Hemorrhage: A Population Pharmacokinetic Approach in Pregnant Individuals. [PDF]

J Clin Pharmacol
Abstract Tranexamic acid (TXA) is used for the treatment and occasionally prevention of postpartum hemorrhage (PPH); however, questions still remain regarding dosing regimen optimization. This study evaluated TXA pharmacokinetic (PK) data from four clinical trials (NCT: 04274335, 03287336, 00872469, and 02797119) conducted in pregnant participants ...
Dunn A, Felfeli M, Seifert SM, Gilliot S, Ducloy-Bouthors AS, Shakur-Still H, Geer A, Grassin-Delyle S, Luban NL, van den Anker JN, Gobburu JVS, Roberts I, Ahmadzia HK.   +12 more
europepmc   +2 more sources

The cost‐effectiveness of tranexamic acid for treatment of postpartum hemorrhage: A systematic review

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2021
Postpartum hemorrhage (PPH) is responsible for nearly one quarter of maternal deaths. A 2017 multicountry trial found that incorporating tranexamic acid (TXA) into the PPH management package was effective in reducing maternal death due to bleeding.
Samia Aziz, Shania Rossiter, C. Homer, Alyce N. Wilson, Liz Comrie-Thomson, N. Scott, Joshua P. Vogel   +6 more
semanticscholar   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source