Results 121 to 130 of about 23,761 (257)

Comparative efficacy and safety of three fixed‐ratio combination products in type 2 diabetes: A network meta‐analysis

Journal of Diabetes Investigation, EarlyView.
Abstract Objective To systematically evaluate and compare the efficacy and safety of three fixed‐ratio combination products—insulin degludec/liraglutide (IDegLira), insulin glargine/lixisenatide (iGlarLixi), and insulin degludec/insulin aspart (IDegAsp)—in patients with type 2 diabetes.
Xiaomei Wang, Jiali Qin, Yang Liu, Xianying Wang   +3 more
wiley   +1 more source

Human metabolic adaptations and prolonged expensive neurodevelopment: A review [PDF]

, 2008
1. After weaning, human hunter-gatherer juveniles receive substantial (≈3.5-7 MJ day^-1^), extended (≈15 years) and reliable (kin and nonkin food pooling) energy provision. 2. The childhood (pediatric) and the adult human ...
John R. Skoyles
core   +2 more sources

Recent advances in incretin biology and therapeutics: From glucose‐dependent insulinotropic polypeptide reappraisal to next‐generation agonists

Journal of Diabetes Investigation, EarlyView.
Future directions in incretin research: Three major directions currently shape therapeutic innovation in incretin research: multi‐receptor agonism, oral drug development, and mechanistic reappraisal of glucose‐dependent insulinotropic polypeptide (GIP) physiology.
Sodai Kubota, Yutaka Seino, Daisuke Yabe
wiley   +1 more source

Explainable cluster-based learning for prediction of postprandial glycemic events and insulin dose optimization in type 1 diabetes.

PLOS Digital Health
Effective management of postprandial glycemic excursions in type 1 diabetes requires accurate prediction of adverse events and personalized insulin adjustments informed by interpretable models. This study presents an explainable dual-prediction framework
Najib Ur Rehman, Ivan Contreras, Aleix Beneyto, Josep Vehi   +3 more
doaj   +1 more source

Examining the Influence of Glycemic Management During Sleep on Sleep‐Related Bruxism: A Pilot Study

Journal of Oral Rehabilitation, EarlyView.
Stabilisation of blood glucose levels during sleep may improve sleep‐related bruxism (SRB), particularly by suppressing sympathetic nervous system activity. Furthermore, it is expected that these findings will lead to the establishment of new treatment methods for SRB in sleep dentistry.
Tatsuya Taniwaki, Kazuo Okura, Yoshitaka Suzuki, Toyoko Tajima, Akitomo Watanabe, Yoshizo Matsuka   +5 more
wiley   +1 more source

Nutrition Strategies for Next‐Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence

Obesity Reviews, EarlyView.
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley, Cara F. Ruggiero, Adrian Brown   +2 more
wiley   +1 more source

Integrating the inputs that shape pancreatic islet hormone release. [PDF]

, 2019
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core  

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

Linking dynamic cerebral autoregulation and inhibitory executive function: Role of modifiable behaviours

Experimental Physiology, EarlyView.
Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley   +1 more source

Insulinoma Presenting With Postprandial Hypoglycemia in a Pregnant Woman With MEN-1. [PDF]

JCEM Case Rep, 2023
Wood AJ, Kasireddy V, Chitturi S, Walsh JP.   +3 more
europepmc   +1 more source