Results 131 to 140 of about 120,482 (333)

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Lactylation: The emerging frontier in post-translational modification

Frontiers in Genetics
Lactate, a metabolic byproduct, has gained recognition as a highly influential signaling molecule. Lactylation, an emerging form of post-translational modification derived from lactate, plays a crucial role in numerous cellular processes such as ...
Zhou Lu, Xueting Zheng, Mingsong Shi, Yuan Yin, Yuanyuan Liang, Zhiyan Zou, Chenghe Ding, Yuanjing He, Yan Zhou, Xiaoan Li, Xiaoan Li   +10 more
doaj   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Structural and Functional Impact of Posttranslational Modification of Glypican-3 on Liver Carcinogenesis. [PDF]

Cancer Res, 2023
Schepers EJ, Glaser K, Zwolshen HM, Hartman SJ, Bondoc AJ.   +4 more
europepmc   +1 more source

Posttranslational Modifications of Tubulin and Cilia [PDF]

, 2016
Dorota Włoga, Ewa Joachimiak, Panagiota Louka, Jacek Gaertig   +3 more
openalex   +1 more source

AlphaFold2 and RoseTTAFold Predict Posttranslational modifications. Chromophore Formation in GFP-like Proteins [PDF]

, 2022
Sophia M. Hartley, Kelly A. Tiernan, Gjina Ametaj, Adriana Cretu, Yan Zhuang, Marc Zimmer   +5 more
openalex   +1 more source

Introduction: Posttranslational Protein Modification [PDF]

Chemical Reviews, 2018
Hening Lin, Kate S. Caroll
openaire   +2 more sources

UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K/AKT Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li, Ning Wang, Fan Jiang, Jie‐Cheng Yang, Yan‐Yun Wang, Kun Wang   +5 more
wiley   +1 more source

Posttranslational modification and heme cavity architecture of human eosinophil peroxidase-insights from first crystal structure and biochemical characterization. [PDF]

J Biol Chem, 2023
Pfanzagl V, Gruber-Grünwald C, Leitgeb U, Furtmüller PG, Obinger C.   +4 more
europepmc   +1 more source