Results 151 to 160 of about 119,060 (284)

Tubulin Posttranslational Modifications and Emerging Links to Human Disease [PDF]

open access: bronze, 2018
Maria M. Magiera   +3 more
openalex   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

New insights into posttranslational modifications of proteins during bull sperm capacitation [PDF]

open access: gold, 2023
Agnieszka Mostek-Majewska   +3 more
openalex   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan   +14 more
wiley   +1 more source

Lactylation: a Passing Fad or the Future of Posttranslational Modification. [PDF]

open access: yesInflammation, 2022
Xin Q   +6 more
europepmc   +1 more source

The economic basis of periodic enzyme dynamics

open access: yes, 2016
Periodic enzyme activities can improve the metabolic performance of cells. As an adaptation to periodic environments or by driving metabolic cycles that can shift fluxes and rearrange metabolic processes in time to increase their efficiency.
Liebermeister, Wolfram
core  

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

open access: yesiMetaOmics, EarlyView.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen   +7 more
wiley   +1 more source

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