Results 261 to 270 of about 119,060 (284)

Posttranslational modification of β-catenin is associated with pathogenic fibroblastic changes in bronchopulmonary dysplasia

, 2016
Jennifer M. S. Sucre, Preethi Vijayaraj, Cody J. Aros, Dan Wilkinson, Manash K. Paul, Bruce Dunn, Susan H. Guttentag, Brigitte N. Gomperts   +7 more
openalex   +2 more sources

TIR innovations in plant immunity

New Phytologist, EarlyView.
Summary Toll/interleukin‐1 receptor (TIR) domain‐containing immune receptors are crucial for plant immunity, with recent advancements highlighting the enzymatic functions of TIR domains and their production of signaling molecules. TIR‐catalyzed compounds interact with receptors to form functional modules that trigger the oligomerization of helper ...
Zhongshou Wu
wiley   +1 more source

Transcriptional outputs and condensates – formation and function

New Phytologist, EarlyView.
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin, Jiawei Li, Mark D. Tully, Xuelei Lai, Chloe Zubieta   +4 more
wiley   +1 more source

SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

New Phytologist, EarlyView.
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue, Jiankun Li, Ya‐Chi Yu, Li‐Qing Chen   +3 more
wiley   +1 more source

CD36 and Its Role in Obesity

Obesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
wiley   +1 more source

Author response: Editing of endogenous tubulins reveals varying effects of tubulin posttranslational modifications on axonal growth and regeneration

Yu-Ming Lu, Shan Yan, Shih-Chieh Ti, Chaogu Zheng   +3 more
openalex   +1 more source

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

RPE65 Palmitoylation: A Tale of Lipid Posttranslational Modification

, 2019
Sheetal Uppal, Eugenia Poliakov, Susan Gentleman, T. Michael Redmond   +3 more
openalex   +2 more sources

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer, Somanath Kallolimath, Richard Strasser   +2 more
wiley   +1 more source