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Posttranslational Modification of Sodium Channels
2017Voltage-gated sodium channels (VGSCs) are critical determinants of excitability. The properties of VGSCs are thought to be tightly controlled. However, VGSCs are also subjected to extensive modifications. Multiple posttranslational modifications that covalently modify VGSCs in neurons and muscle have been identified.
Yanling Pan +2 more
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Posttranslational protein modifications
Critical Care Medicine, 2005Hülya Bayır +2 more
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Posttranslational modification of MDM2.
Molecular cancer research : MCR, 2004The functions of the MDM2 protein, in particular its E3 ubiquitin ligase activity and its ability to interact with a number of cellular proteins intimately involved in growth regulation, are modulated by sumoylation and multisite phosphorylation. These posttranslational mechanisms not only regulate the intrinsic activity of MDM2 in response to cellular
Meek, David W, Knippschild, Uwe
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Proteome Analysis of Posttranslational Modifications
2003Publisher Summary The chapter focuses on current progress in the identification of protein modifications, with an emphasis on phosphorylation and glycosylation. One of the most important posttranslational protein modifications used to modulate protein activity and propagate signals within cellular pathways and networks is phosphorylation.
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13 Posttranslational Modifications of Secretory Proteins
1998Publisher Summary This chapter focuses on post-translational modifications of secretory proteins. Proteins that traverse the secretory pathway and reach the plasma membrane may be targeted to various locations. One final destination is the plasma membrane itself.
Klis, F.M. +8 more
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Posttranslational Modification
2013At the later stages of protein biosynthesis, after their transcription, many proteins undergo intensive chemical alterations, collectively known as protein posttranslational modifications (PTMs). These modifications are many and range from the proteolytic cleavage to the covalent attachment of diverse functional groups or even proteins to specific side
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Posttranslational Modification of Proteins
2010Keith D. Green, Sylvie Garneau-Tsodikova
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