Results 91 to 100 of about 32,301 (303)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Chronic low back pain and postural instability: interaction effects of pain severity, age, BMI, and disability

open access: yesFrontiers in Public Health
ObjectivesThis study aimed to (1) compare postural sway patterns between individuals with chronic low back pain (CLBP) and asymptomatic controls, (2) evaluate correlations between pain severity and postural stability variables, and (3) assess the ...
Adel Alshahrani   +2 more
doaj   +1 more source

The influence of horizontally rotating sound on standing balance [PDF]

open access: yes, 2014
International audiencePostural control is known to be the result of the integration and processing of various sensory inputs by the central nervous system.
Bourdin, Christophe   +3 more
core   +2 more sources

Warming summers limit reindeer grazing, weakening herbivory pressure in the mountain tundra

open access: yesEcography, EarlyView.
Climate change is predicted to alter species interactions by exposing ecosystems to increasingly frequent and intense warm spells. In the mountain tundra, grazing by large herbivores, particularly reindeer, can limit shrub expansion and preserve Arctic plant diversity.
Marianne Stoessel   +2 more
wiley   +1 more source

Triboelectric–Electromagnetic Generator‐Enabled Hybrid Power Backpack for Self‐Powered Field Safety Management

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A lightweight hybrid backpack integrating SC‐TENGs and R‐EMGs harvests biomechanical energy during walking. With a low activation speed of 3 km h−1 and a high specific power of 0.18 W kg−1, it enables self‐powered field safety management. The power backpack refers to an energy‐harvesting solution engineered to mitigate battery reliance in wearable ...
Jie Chen   +6 more
wiley   +1 more source

Ictal semiology in precuneus seizures: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To evaluate the ictal semiology in seizures originating in the precuneus and to help guide seizure interpretation within the framework of presurgical evaluation. Methods This systematic review followed a Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and a Quality Assessment tool for Diagnostic Accuracy ...
Erika Ignatius   +8 more
wiley   +1 more source

Anthropologist, heal thyself: Toward an anthropology of healing through relational interbeing

open access: yesFeminist Anthropology, EarlyView.
Abstract I call for an anthropology that confronts its own woundedness. Anthropologists often bear witness to suffering but rarely examine how our own grief, trauma, and institutional distress shape the affective tone of our work. Drawing on fieldwork with Runa (Quechua) women affected by forced sterilization in Peru and guided by my collaborator and ...
Lucía Isabel Stavig
wiley   +1 more source

Older adults and individuals with Parkinson’s disease control posture along suborthogonal directions that deviate from the traditional anteroposterior and mediolateral directions

open access: yesScientific Reports
A rich and complex temporal structure of variability in postural sway characterizes healthy and adaptable postural control. However, neurodegenerative disorders such as Parkinson’s disease, which often manifest as tremors, rigidity, and bradykinesia ...
Madhur Mangalam   +6 more
doaj   +1 more source

ISway: a sensitive, valid and reliable measure of postural control [PDF]

open access: yes, 2012
BACKGROUND: Clinicians need a practical, objective test of postural control that is sensitive to mild neurological disease, shows experimental and clinical validity, and has good test-retest reliability. We developed an instrumented test of postural sway
Arash Salarian   +6 more
core   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

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