Results 61 to 70 of about 100,974 (304)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle

, 2011
Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Verstegen, M.W.A., Martin W. A. Verstegen, Martin-Tereso Lopez, J., Javier Martín-Tereso   +3 more
core   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Effects of sodium zirconium cyclosilicate on the quality of life of patients with hyperkalemia undergoing hemodialysis: Y-QOL study design

BMC Nephrology
Patients undergoing hemodialysis (HD) face severe dietary potassium restrictions, reducing their quality of life (QOL) and potentially worsening their prognosis.
Shiori Yoshimura, Daisuke Kanai, Hiromichi Wakui, Rika Furuta, Shunichi Fukuhara, Sayaka Shimizu, Kouji Yamamoto, Yusuke Saigusa, Masaaki Hanaoka, Hiroshi Mitsuhashi, Tomoyuki Kawano, Mari Katsumata, Satoshi Yamaguchi, Nariaki Ogawa, Masato Ohsawa, Kohji Ohki, Masahiro Nishihara, Sho Kinguchi, Kengo Azushima, Tomohiko Kanaoka, Yusuke Kobayashi, Yoshiyuki Toya, Takeo Ishii, Ashio Yoshimura, Gen Yasuda, Tadashi Kuji, Toshimasa Ohnishi, Kouichi Tamura   +27 more
doaj   +1 more source

Reduction of potassium content of green bean pods and chard by culinary processing. Tools for chronic kidney disease

Nefrología (English Edition), 2016
Introduction: In order to prevent a possible hyperkalemia, chronic renal patients, especially in advanced stages, must follow a low potassium diet. So dietary guidelines for chronic kidney disease recommend limiting the consumption of many vegetables, as
Montserrat Martínez-Pineda, Cristina Yagüe-Ruiz, Alberto Caverni-Muñoz, Antonio Vercet-Tormo   +3 more
doaj   +1 more source

Ciclopirox Olamine Inhibits the NLRP3 Inflammasome to Alleviate Inflammatory Diseases

Advanced Science, EarlyView.
There is no drug targeting the NLRP3 inflammasome that has been approved for use in clinical settings. Ciclopirox olamine (CPX), an antifungal agent approved by the US Food and Drug Administration (FDA), is identified as a specific and potent NLRP3 inflammasome inhibitor. CPX targets the NACHT domain of NLRP3 at Y381 to impair NLRP3 oligomerization and
Xinyu Xia, Hui You, Ke Zhang, Hui Jiang, Hongping Liu, Lianghua Liu, Aijie Zhang, You Zhou   +7 more
wiley   +1 more source

High sodium intake does not worsen low potassium‐induced kidney damage

Physiological Reports, 2023
High sodium and low potassium intake have both been linked to poor cardiovascular health outcomes and increased mortality rates. A combination of the two is thought to be particularly detrimental. While mechanisms are multiple, the kidney is an important
Yahua Zhang, Juan Pablo Arroyo, Fabian Bock, Ming‐Zhi Zhang, Raymond C. Harris, Andrew S. Terker   +5 more
doaj   +1 more source

Assessment of dietary sodium, potassium and sodium-potassium ratio intake by 72 h dietary recall and comparison with a 24 h urinary sodium and potassium excretion in Dominican adults

[Background] PAHO-WHO reports that sodium intake is currently high in the Caribbean. The objective was to estimate sodium (Na) and potassium (K) intakes by 72 h dietary recall and compare them with those obtained from 24 h urinary excretion in Dominican ...
Garcia Lithgow, Carlos H., Durán-Cabral, Madeline, Olmedilla-Alonso, Begoña, García-Estrella, Kilsaris, Estévez Santiago, Rocío, Madeline Durán-Cabral, Rocío Estévez-Santiago, Alexandra Winter-Matos, Carlos H. García-Lithgow, Begoña Olmedilla-Alonso, Winter-Matos, Alexandra, Durán Cabral, Madeline, Garcia Estrella, Kilsarys, Kilsaris García-Estrella, García-Lithgow, Carlos H., Estévez-Santiago, Rocío   +15 more
core   +1 more source

Dietary Potassium Attenuates the Effects of Dietary Sodium on Vascular Function in Salt-Resistant Adults

, 2020
The influence of dietary sodium and potassium on blood pressure (BP) has been extensively studied, however their impact on endothelial function, particularly any interactive effects, has received less attention. The purpose of this study was to determine
Alexis Mbakwe, William B. Farquhar, Katarina Smiljanec, Shannon L. Lennon, Macarena Ramos Gonzalez   +4 more
core   +1 more source