Results 61 to 70 of about 895,689 (308)

Dietary potassium intake, kidney function, and survival in a nationally representative cohort [PDF]

, 2022
BACKGROUND: In healthy adults, higher dietary potassium intake is recommended given that potassium-rich foods are major sources of micronutrients, antioxidants, and fiber.
Connie M Rhee, You, Amy, Mackenzie K Cervantes, Cervantes, Mackenzie, Daza, Andrea, Kovesdy, Csaba, Shaista Malik, Kalantar-Zadeh, Kamyar, Yoko Narasaki, Csaba P Kovesdy, Narasaki, Yoko, Andrea Daza, Kamyar Kalantar-Zadeh, Malik, Shaista, Linda W Moore, Amy S You, Moore, Linda, Bross, Rachelle, Danh V Nguyen, Rachelle Bross, Rhee, Connie, Nguyen, Danh   +21 more
core   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Quantifying mineral sources of potassium in agricultural soils [PDF]

, 2008
Soil potassium (K) reserves are crucial for crop quality and yield in low input agricultural systems. Soils contain varying amounts of K-bearing minerals and differ in their inherent K supply capacity.
Andrist Rangel, Ylva
core   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Associations between dietary potassium intake and urinary potassium excretion: a protocol for systematic review and meta-analysis

Systematic Reviews
Background While numerous studies have reported associations between low dietary potassium intake and adverse clinical outcomes, methods to estimate potassium intake, mainly self-reported dietary measures and urinary potassium excretion, entail certain ...
Nobuhisa Morimoto, Hasan Jamil, Mohab Alakkari, Yuki Joyama, Tatsuhiko Anzai, Kunihiko Takahashi, Soichiro Iimori   +6 more
doaj   +1 more source

Dietary intake and nutritional adequacy prior to conception and during pregnancy: a follow-up study in the north of Portugal. [PDF]

, 2008
OBJECTIVE: To assess maternal diet and nutritional adequacy prior to conception and during pregnancy. DESIGN: Follow-up of a cohort of pregnant women with collection of questionnaire data throughout pregnancy and after delivery.
Barros, Henrique, Pinto, Elisabete, dos Santos Silva, Isabel   +2 more
core   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Effects of sodium zirconium cyclosilicate on the quality of life of patients with hyperkalemia undergoing hemodialysis: Y-QOL study design

BMC Nephrology
Patients undergoing hemodialysis (HD) face severe dietary potassium restrictions, reducing their quality of life (QOL) and potentially worsening their prognosis.
Shiori Yoshimura, Daisuke Kanai, Hiromichi Wakui, Rika Furuta, Shunichi Fukuhara, Sayaka Shimizu, Kouji Yamamoto, Yusuke Saigusa, Masaaki Hanaoka, Hiroshi Mitsuhashi, Tomoyuki Kawano, Mari Katsumata, Satoshi Yamaguchi, Nariaki Ogawa, Masato Ohsawa, Kohji Ohki, Masahiro Nishihara, Sho Kinguchi, Kengo Azushima, Tomohiko Kanaoka, Yusuke Kobayashi, Yoshiyuki Toya, Takeo Ishii, Ashio Yoshimura, Gen Yasuda, Tadashi Kuji, Toshimasa Ohnishi, Kouichi Tamura   +27 more
doaj   +1 more source

A multicentral prospective cohort trial of a pharmacist-led nutritional intervention on serum potassium levels in outpatients with chronic kidney disease: The MieYaku-Chronic Kidney Disease project.

PLoS ONE
Although dietary potassium restriction is an acceptable approach to hyperkalemia prevention, it may be insufficient for outpatients with chronic kidney disease (CKD).
Yuki Asai, Asami Muramatsu, Tatsuya Kobayashi, Ikuhiro Takasaki, Toshiki Murasaka, Ai Izukawa, Kahori Miyada, Takahiro Okazaki, Tatsuki Yanagawa, Yasuharu Abe, Yasushi Takai, Takuya Iwamoto   +11 more
doaj   +1 more source