Results 71 to 80 of about 1,168,838 (301)
In addition to the classic and well-established “feedback control” of potassium balance, increasing investigative attention has focused on a novel and not widely recognized complementary regulatory paradigm for maintaining potassium homeostasis—the “feed-
Murray Epstein, Meyer D. Lifschitz
doaj +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
The structure of a voltage gated potassium channel
Voltage gated potassium channels (Kv channels) are tetrameric ion channels, responsible for regulating the potassium component of the membrane potential in a large range of cell types ranging from mammalian excitable cells to bacteria. Attempts have been
Rogers, Nik
core +1 more source
The mineral content of biomass plays an important role in the gasification rate of biomass-derived char. The understanding and quantification of mineral-related phenomena are thus of importance when considering gasification reactor design. In the present
Efthymios Kantarelis +5 more
core +1 more source
Haemodynamic consequences of changing potassium concentrations in haemodialysis fluids
Background A rapid decrease of serum potassium concentrations during haemodialysis produces a significant increase in blood pressure parameters at the end of the session, even if effects on intra-dialysis pressure are not seen.
Lucchini Barbara +4 more
doaj +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes [PDF]
We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Jowett, AJ +7 more
core
Pharmacological Approaches to Studying Potassium Channels
In this review, we consider the pharmacology of potassium channels from the perspective of these channels as therapeutic targets. Firstly, we describe the three main families of potassium channels in humans and disease states where they are implicated ...
Alistair Mathie +12 more
core +1 more source
LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux
Ca2+ transport across the inner membrane of mitochondria (IMM) is of major importance for their functions in bioenergetics, cell death and signaling. It is therefore tightly regulated.
Shane Austin +8 more
doaj +1 more source
Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang +7 more
wiley +1 more source

