Results 21 to 30 of about 4,895 (115)

Assessing the Worth of Noble Gas Tracer Concentrations in Alluvial River‐Aquifer Systems Using Data Space Inversion

Water Resources Research, Volume 62, Issue 7, July 2026.
Abstract Alluvial systems are dynamic, structurally complex environments. Groundwater that is extracted from these systems is widely used for domestic consumption. Numerical models play an important role in the management of this extraction. To provide support for decision‐making, models must assimilate data that inform the spatial and temporal ...
Hugo Delottier, Morgan Peel, John Doherty, Oliver S. Schilling, Philip Brunner   +4 more
wiley   +1 more source

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, Volume 5, Issue 3, June 2026.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

Lunar Crustal Formation by Melt Migration and Differentiation Within a Stagnant Lid

Journal of Geophysical Research: Planets, Volume 131, Issue 6, June 2026.
Abstract The lunar anorthosite highlands represent the Moon's primary crust, which formed during the solidification of a magma ocean following the Moon‐forming giant impact. However, the canonical model of anorthite flotation in the crystallizing magma ocean often struggles to reproduce the long > ${ >} $200 Myr solidification timescale required by the
K. H. Dodds, C. Michaut, J. A. Neufeld
wiley   +1 more source

A Phase 1 Oral Mass Balance and Combined Intravenous [14C] Microtracer Study to Characterize the Absorption, Metabolism, Excretion, and Pharmacokinetics of Antitumor Drug E7386 in Humans

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract E7386, an orally active protein‐protein interaction inhibitor, is reported to impair the interaction between transcriptional co‐activator CREB‐binding protein and β‐catenin. A competent study design exploring the concomitant dosing routes, sensitive intravenous (IV; [14C]) microtracer technology, and oral [14C] radiolabeled dosing was ...
Shriram M. Pathak, Nozomi Hayata, Takashi Ueno, Jagadeesh Aluri, Jincao Wu, Ashley S. Brooks, Catherine M. Laing, Lea Dutta, Sanae Yasuda   +8 more
wiley   +1 more source

A Scoping Review of Thermal and Nonthermal Technologies for Listeria monocytogenes Inactivation in Ready‐to‐Eat Meats

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Listeria monocytogenes continues to present a significant food safety challenge in ready‐to‐eat (RTE) products, despite existing regulatory standards and antimicrobial intervention strategies. To manage the risk of L. monocytogenes in RTE meats, food producers and researchers have explored a range of intervention strategies, broadly ...
Mustafa Guzel, Ilhami Okur
wiley   +1 more source

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

Volcanic History of Rodrigues Island and Its Relationship With the Central Indian Ridge and the Réunion Hotspot

Geochemistry, Geophysics, Geosystems, Volume 27, Issue 4, April 2026.
Abstract Many intraplate volcanic chains are explained as hotspot trails formed by plate motion over mantle plumes, yet some deviate from this model. The Rodrigues Ridge, a volcanic lineament extending eastward from the Réunion hotspot track toward the Central Indian Ridge (CIR), is one such case.
Julien Seghi, Vincent Famin, Xavier Quidelleur, Loraine Gourbet, Martin Danišík, Axel K. Schmitt, François Nauret, Sidonie Revillon, Maëlis Arnould, Laurent Michon, Reshad Jhangeer‐Khan   +10 more
wiley   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Eocene Lamproitic Magmatism in Gangdese: Melting Sub‐Arc Lithospheric Mantle and Implications for the Early Cenozoic Magmatic “Flare Up” in Southern Tibet

Geochemistry, Geophysics, Geosystems, Volume 27, Issue 3, March 2026.
Abstract The role of sub‐arc mantle lithosphere in the build‐up of a batholith is an outstanding issue that is still not well resolved. Lamproite is a mantle‐derived magmatic rock that provides a window to learn the composition and the enrichment processes of subcontinental lithospheric mantle (SCLM).
Y. H. Tian, L. S. Zeng, L. H. Zhao, L. L. Yan, G. X. Li   +4 more
wiley   +1 more source

Magnetic Evolution of Super‐Earth Exoplanets With a Basal Magma Ocean

Journal of Geophysical Research: Planets, Volume 131, Issue 3, March 2026.
Abstract Habitability of super‐Earths likely requires self‐sustained magnetic fields to shield their atmospheres from stellar forcing. Extreme pressures and temperatures probably produce a long‐lived basal magma ocean (BMO), a potential source for these fields.
Victor Lherm, Miki Nakajima, Eric G. Blackman   +2 more
wiley   +1 more source