Results 291 to 300 of about 583,846 (360)

Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth. [PDF]

Vaccines (Basel)
França CT, Pletnev S, Madan B, Katsamba PS, McKee K, Morano NC, Zhang B, Bahna F, Bylund T, Lin BC, Louder MK, Mannepalli S, Nimrania R, O'Dell S, Doria-Rose NA, Kwong PD, Shapiro L, Sheng Z, Zhou T, DeKosky BJ.   +19 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Discovery of Lenacapavir: First-in-Class Twice-Yearly Capsid Inhibitor for HIV-1 Treatment and Pre-exposure Prophylaxis. [PDF]

J Med Chem
Canales E, Tse W, Schroeder SD, Chou CH, Liu Q, Zhang J, Lazerwith SE, Morganelli P, Saito RD, Brizgys G, Li J, Wu Q, Graupe M, Halcomb RL, Desai M, Cannizzaro C, Hu E, Perry JK, Villaseñor AG, Somoza JR, Ferrao RD, Swaminathan S, Zheng J, Lu B, Mwangi J, Wang K, Subramanian R, Smith BJ, Rhodes G, Rowe W, Sauer D, Lad L, Papalia GA, Clancy S, Stepan GJ, Yu H, Sakowicz R, Shi B, Carr G, Bam RA, Tsai LK, Singer E, Hansen D, Mulato A, Yant SR, Cihlar T, Link JO.   +46 more
europepmc   +1 more source

Structural Insights into the SARS-CoV-2 Spike Protein and Its Implications for Antibody Resistance. [PDF]

Biomolecules
Yamamoto Y, Noguchi K.
europepmc   +1 more source

Radical Prostatectomy Following Holmium Laser Enucleation of the Prostate (HoLEP): A Systematic Review of Perioperative, Oncological, and Functional Outcomes. [PDF]

Cancers (Basel)
Katsimperis S, Tzelves L, Markopoulos T, Bellos T, Douroumis K, Kostakopoulos N, Skolarikos A.   +6 more
europepmc   +1 more source

Inhibitory Potency of a Plant-Based Zinc Protoporphyrin on Heme Oxygenase Activity.

Neonatology
Muchová L, Reddy GSKK, Wells GS, Zhao H, Vreman HJ, Wong RJ, Stevenson DK.   +6 more
europepmc   +1 more source

Discovery of an allosteric binding site for anthraquinones at the human P2X4 receptor. [PDF]

Nat Commun
Nagel J, Namasivayam V, Weinhausen S, Sierra-Marquez J, Baqi Y, Al Musawi HAM, Abdelrahman A, Vaaßen VJ, Schlegel JG, Taplick L, Torp J, Kubicek J, Maertens B, Geyer M, Claff T, Nicke A, Hagelueken G, Müller CE.   +17 more
europepmc   +1 more source

Therapeutic effects of vitamin D and omega-3 supplementation on HFHS diet-induced endothelial dysfunction in Wistar rats. [PDF]

Curr Res Pharmacol Drug Discov
Le Jan D, Destrumelle S, Thorin C, Desfontis JC, Betti E, Mallem MY.   +5 more
europepmc   +1 more source

Schweinfurthins and their analogues are highly selective cellular probes for oxysterol-binding protein (OSBP). [PDF]

RSC Med Chem
Depta L, He N, Madsen ML, Nielsen MLH, Bryce-Rogers HP, Waterworth SC, Neighbors JD, Stockdale DP, Callahan MP, Mente NR, Wiemer DF, Beutler JA, Laraia L.   +12 more
europepmc   +1 more source

Polycyclic Aromatic Hydrocarbons (16PAHs) Residue and Potency Equivalency Factor in Edible tissue of Cyprinus Carpio from Caspian Sea

, 2014
Hassan Nasrollahzadeh Saravi, Horieh Unesipour, Nima Pourang   +2 more
openalex   +1 more source