Results 51 to 60 of about 1,009,444 (403)

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Epitope Profiling of SARS-CoV-2 Spike Antigen Provides a Novel Strategy for Developing ELISAs Specific for Different Spike Protein Variants in Bivalent Vaccine Formulations

Vaccines
Background/Objectives: An initial COVID-19 candidate vaccine containing a purified ancestral SARS-CoV-2 spike antigen was characterized with an ELISA using recombinant monoclonal antibodies (mAbs) generated against this variant.
Luciano Ettorre, Trevor Williams, Camille Houy, Shaolong Zhu, Michael Kishko, Ali Azizi, Andrew D. James, Beata Gajewska, Jason Szeto   +8 more
doaj   +1 more source

Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency

PLoS ONE, 2019
Doxorubicin is a chemotherapeutic agent that is commonly used to treat a broad range of cancers. However, significant cardiotoxicity, associated with prolonged exposure to doxorubicin, limits its continued therapeutic use.
Christina E. M. Schindler, Andie Collinson, Carl Matthews, A. Pointon, Lesley Jenkinson, R. Minter, T. Vaughan, N. Tigue   +7 more
semanticscholar   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Ius sive potentia: Paul and Spinoza [PDF]

Filozofija i Društvo, 2020
This article is a part of a research project entitled Law as Potency, that, broadly put, investigates the relation between law and ontology. I argue, starting from St. Paul, that an ontological perspective can be understood as the possibility of
Milović Miroslav
doaj   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H., Ballestrero A., Bellamy W. T., Betanzos-Lara S., Bozic I., Bushra Qamar, Carew J. S., Castonguay A., Chan J., Constantini P., Dai Y., Degterev A., Dindo D., Doroshow J. H., Dyke M. W. Van, Fagan V., Finnilä S., Frank J. E., Fu Y., Fu Y., Gaiddon C., Garbutcheon-Singh K. B., Hannon M. J., Hartinger C. G., Hileman E. A., Holbeck S., Huo H., Ian Hands-Portman, Isolda Romero-Canelón, Jessica M. Hearn, Jordan M. A., Jungwirth U., Kelland L., Kerr J. F., Kroemer G., Lazebnik Y. A., Liu Z., Liu Z., Liu Z., Lu J.-J., McKeage M. J., Millar A. W., Monneret C., Nagata S., Park G. Y., Paull K., Perchellet E. M., Peter J. Sadler, Petrelli A., Pittella F., Porteous C. M., Pracharova J., Purewal M., Rai S. S., Rixe O., Saraste A., Shoemaker R. H., Shoemaker R. H., Siddik Z., Sidler D., Tsutsui T., Türk D., Van den Bogert C., Zalacaín M., Zhang Y.-W., Zhe Liu, Zhou D.-F., Zhu Z.   +67 more
core   +1 more source

Increasing potency and price of cannabis in Europe, 2006–16

Addiction, 2019
Aims To quantify changes in (i) potency (concentration of Δ9‐tetrahydrocannabinol; %THC), (ii) price (euros/g of cannabis) and (iii) value (mg THC/euro) of cannabis resin and herbal cannabis in Europe. Design Repeated cross‐sectional study.
T. Freeman, Teodora Groshkova, A. Cunningham, R. Sedefov, P. Griffiths, M. Lynskey   +5 more
semanticscholar   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

EVALUATION OF POTENCY OF MUMPS VACCINE USED IN IRAN: COMPARISON OF WHO AND NIBSC METHOD IN CELL CULTURE [PDF]

Acta Medica Iranica, 2005
Vaccination against mumps is included in world Health Organization (WHO) program of global immunization. Safety and efficacy of vaccines must be confirmed by control units in charge of public health.
S. Tavajohi, H. Rastegar, S. N. Ostad, S. M. Rezayat M. H. Ghahramani   +3 more
doaj  

STUDI POTENSI TOLERANSI ISOLAT FUNGI LIMBAH COMBERAN \ud TERHADAP DETERGEN, SABUN MANDI DAN SABUN COLEK KAWASAN \ud PADAT HUNI DI KOTA MALANG [PDF]

, 2008
Detergent and Soap is cleanser of sintetic having negative impact to health either through is direct (physical contact) and also indirectly (residing in nature or environment in the form of waste).
Su’udiyah, Sulfi
core