Results 221 to 230 of about 36,575,751 (379)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Global health burdens of plastics: a lifecycle assessment model from 2016 to 2040.

Lancet Planet Health
Deeney M, Hamelin L, Vialle C, Yan X, Green R, Yates J, Kadiyala S.   +6 more
europepmc   +1 more source

A Non-Contact Electrostatic Potential Sensor Based on Cantilever Micro-Vibration for Surface Potential Measurement of Insulating Components. [PDF]

Sensors (Basel)
Chen C, Zhou R, Zhang Y, Li Y, Wang Q, Liu P, Peng Z.   +6 more
europepmc   +1 more source

Antioxidant and antimicrobial potentials of functional food Arum Dioscoridis

Mansur Seymen Seğmenoğlu
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping Potential. [PDF]

Rapid Commun Mass Spectrom
Möller T, Krug O, Thevis M.
europepmc   +1 more source

The Environmental Sustainability Potential of Autonomous Vehicles: An Overview

Herman Szűcs, Jozefin Szűcs
openalex   +2 more sources

A concept of potential future-gen radio spectrum administration seeking easy access spectrum paradigm figured on signal to interference noise ratio and interference thresholds

, 2015
M. Ahsan Kabir, MA Sobhan, M Qasim Khan, Faheem Ahmed, MN Nabi   +4 more
openalex   +2 more sources

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2014
C. Franceschi, J. Campisi
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source