Results 41 to 50 of about 84,179 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Cognitive proximity for innovation: Why matters? an applied analysis.

open access: yesPLoS ONE, 2023
The purpose of this research is to deepen the study of the influence of cognitive proximity has on the innovative performance of firms, as well as the mediating effect of potential and realized absorptive capacity in this relationship.
Eduardo Sánchez-García   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Absorptive capacity and the diffusion of innovation in NTBFs and startups: A study in the Brazilian Federal District

open access: yesRegepe Entrepreneurship and Small Business Journal, 2023
Purpose: To verify the contribution of the Absorptive Capacity (ACAP) to the diffusion of innovation in New Technology-Based Firms (NTBFs) and startups in the Brazilian Federal District.
Bruno Alencar Pereira   +1 more
doaj   +1 more source

The development of absorptive capacity-based innovation in a construction SME [PDF]

open access: yes, 2010
Traditionally, construction has been a transaction-oriented industry. However, it is changing from the design-bid-build process into a business based on innovation capability and performance management, in which contracts are awarded on the basis of ...
Colenso M.   +12 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Linking Transformational Leadership, Absorptive Capacity, and Corporate Entrepreneurship

open access: yesAdministrative Sciences, 2018
This study aims to analyze the nexus between transformational leadership and corporate entrepreneurship through an integration of dispersed scholarly work on transformational leadership, absorptive capacity, and corporate entrepreneurship under one ...
Imran Shafique, Masood Nawaz Kalyar
doaj   +1 more source

Analyzing an absorptive capacity: unlearning context and information sistem capabilities as catalysts for innovativeness [PDF]

open access: yes, 2010
This study examines the impact of a company’s unlearning context and information system (IS) capabilities on the company’s ability to challenge of basic beliefs and to implement processes that are explicitly or tacitly helpful in the reception of new ...
Cegarra-Navarro, Juan Gabriel   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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