Results 71 to 80 of about 1,057,490 (313)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
PhysicsWe investigate time-resolved wave-packet transport in monolayer graphene patterned with asymmetric arrays of circular electrostatic scatterers. Using the Dirac continuum model with a split-operator scheme, we track how transmission evolves with scatterer
Khakimjan Butanov +6 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Theory of Electron Transport in Two-Barrier Five-Layer Semiconductor Structures
East European Journal of PhysicsThe dependence of the transparency coefficient of a five-layer two-barrier structure on the electron energy and the ratio of the widths of two neighboring potential barriers is calculated.
Rustam Y. Rasulov +4 more
doaj +1 more source
Results in Materials, 2020 This work has been done to study the barrier potential and charge trapping effect of two organic devices which comprises Phenosafranin and Crystal Violet dye respectively and to estimate the influence of Titanium Dioxide (TiO2) nanomaterials in particle ...
Sudipta Sen, N.B. Manik
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Vulnerability of Great Barrier Reef plankton to climate change
, 2007 Our approach here is to examine potential ways that climate change may alter plankton communities of the GBR in the future, focusing on the physical mechanisms that currently drive plankton productivity and composition.
Richardson, A. J. +7 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The effect of potential barrier on stopping power along axis- channel of silicon for protons [PDF]
مجله علوم و فنون هستهای, 2015 In this paper, the effect of the potential barrier and open area of Silicon along the crystallographic direction and on the channeling stopping power and the channeling half- distance for protons are investigated.
Sepideh Shafiei, Mohammad Lamehi-Rashti
doaj
Location of resonances generated by degenerate potential barrier
Electronic Journal of Qualitative Theory of Differential Equations, 2006 We study resonances of the semi-classical Schrödinger operator $H = -h^2 \Delta + V$ on $L^2(\mathbb{R}^N)$. We consider the case where the potential $V$ have an absolute degenerate maximum. Then we prove that $H$ has resonances with energies $E = V_0 +
H. Baklouti, M. Mnif
doaj +1 more source