Results 61 to 70 of about 1,861,347 (260)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
STUDY ON INTERACTION NATURE OF CANVAS CONVEYER PICK-UP FINGERS WITH ROLL IN PICKUP ZONE
For the purpose of revealing the causes of grain loss after the canvas conveyer pick-up with roll, the interaction nature of its fingers in the pickup zone is determined.
Stanislav M. Krasnostup +2 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Energy potentials of military buildings [PDF]
The economic crisis, extremely large budgets for providing necessary energy and the adopted legislation in the field of energy impose the necessity of finding and implementing positive solutions in order to achieve a proper and desirable degree of energy efficiency.
ZIVKOVIC MILADIN Z., BANJAC GORAN M.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This paper presents a novel rotary electromagnetic actuator designed for high-speed and high-precision positioning with ultra-low power consumption, intended for industrial and scientific applications such as rotary index tables, pick and place robots ...
M. Albertos-Cabanas +4 more
doaj +1 more source
PLAYING WITH A CHAIN OR PHYSICAL AND MATHEMATICAL INFORMATICS
The article describes an educational laboratory work within the framework of interdisciplinary connec- tions at the intersection of informatics, mathematics and physics: the study of the sagging of a closed chain with different support points.
Valery F. Ochkov, Massimiliano Nori
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source

