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A group exhibition of contemporary artists at St. Margaret's House, Edinburgh, February 2014. The exhibition was the first public outing of 'Still Future', a group of eight contemporary artists working with a variety of media and challenging mainstream
Still Future, Fowler, Martin
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
This report provides a snapshot of our world at the start of 2020, helping to make sense of the state of this unique biophysical human ecosystem we inhabit as a planetary changing species.
Future Earth
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Lead Exposure and Prevention Advisory Committee (LEPAC) : 2022 annual report to U.S. Department of Health and Human Services [PDF]
The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research and federal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...
core
Microplastics (MPs) is defined as plastic particles less than 5 mm. MPs have become a major environmental pollutant and it is originating from the breakdown of larger plastic waste.
Sakuntala Nadarasan +7 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Simulated climate change conditions unveil the toxic potential of the fungicide pyrimethanil on the midge Chironomus riparius : a multigeneration experiment [PDF]
Although it has been suggested that temperature increase may alter the toxic potential of environmental pollutants, few studies have investigated the potential risk of chemical stressors for wildlife under Global Climate Change (GCC) impact. We applied a
Diogo, Joao B. +11 more
core +1 more source
The pervasive environmental presence of micro- and nanoplastics (MNPs), combined with their ability to cross biological barriers and accumulate in the brain, has raised significant concerns regarding their neurotoxic potential.
Donato Morena +7 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

