Results 51 to 60 of about 1,454,738 (292)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
IEEE Access, 2017 This paper investigates the problem of almost blank subframe (ABS)-slot access in the heterogeneous networks to optimize network performance under the ABS scheme.
Kailing Yao +3 more
doaj +1 more source
Dimension Four Wins the Same Game as the Standard Model Group
, 2013 In a previous article Don Bennett and I looked for,found and proposed a game in which the Standard Model group S(U(2)XU(3)) gets singled out as the "winner".
Nielsen, H. B.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Interference Mitigation for Coexisting Wireless Body Area Networks: Distributed Learning Solutions
IEEE Access, 2020 When multiple wireless body area networks (WBANs) exist in close proximity to each other, the inter-user interference considerably degrades the signal to interference plus noise ratio of the packets arriving at each WBAN coordinator.
Emy Mariam George, Lillykutty Jacob
doaj +1 more source
A Characterization of Ordinal Potential Games [PDF]
Games and Economic Behavior, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Voorneveld, M., Norde, H.W.
openaire +4 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Mean-Potential Law in Evolutionary Games [PDF]
Physical Review Letters, 2018 The Letter presents a novel way to connect random walks, stochastic differential equations, and evolutionary game theory. We introduce a new concept of potential function for discrete-space stochastic systems. It is based on a correspondence between one-dimensional stochastic differential equations and random walks, which may be exact not only in the ...
Nałęcz-Jawecki, Paweł +1 more
openaire +3 more sources
, 2009 Massive multiplayer online role-playing games (MMORPGs) are very popular in China, which provides a potential platform for scientific research. We study the online-offline activities of avatars in an MMORPG to understand their game-playing behavior.
Jiang, Zhi-Qiang +2 more
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source