Evaluation of the Effect of Food and Formulation on the Pharmacokinetics of the SHP2 Inhibitor Migoprotafib Within a Phase I Study in Cancer Patients. [PDF]
Clin Transl SciSuchomel J +11 more
europepmc +1 more source
A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening
Advanced Materials, EarlyView.A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder +3 more
wiley +1 more source
Compact Optical Visual Magnification System with a Wide Field of View. [PDF]
Sensors (Basel)Milman U, Kaufmann J, Arieli Y.
europepmc +1 more source
Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications
Advanced Materials, EarlyView.Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa +14 more
wiley +1 more source
Directional Flow of Confined Polaritons in CrSBr
Advanced Materials, EarlyView.CrSBr, a layered magnetic semiconductor, naturally channels self‐hybridized excitonpolaritons into highly directional flow. Its intrinsic optical anisotropy, high refractive index, and strong lightmatter coupling enable long‐range guided modes along the a‐axis, with propagation lengths set by their excitonphoton admixture.
Pratap Chandra Adak +10 more
wiley +1 more source
Objective Assessment of the Onset of RelabotulinumtoxinA in the Elevation of the Eyebrow and Its Clinical Implications. [PDF]
J Cosmet DermatolDi Gregorio C +7 more
europepmc +1 more source
A Biochar‐Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis
Advanced Materials, EarlyView.This work presents the synthesis of a polyacrylamide hydrogel wherein biomass‐derived biochar is co‐encapsulated with the enzyme horseradish peroxidase (HRP). The resulting composite hydrogel possesses balanced electron‐rich and electron‐deficient domains, creating an optimal microenvironment that concentrates both hydrogen peroxide and phenol ...
Shengzhe Wang +9 more
wiley +1 more source
Advanced Materials, EarlyView.Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam +6 more
wiley +1 more source
Five decades of total ankle replacement: from early failures to fourth-generation innovations and future priorities. [PDF]
Eur J Orthop Surg TraumatolColò G +5 more
europepmc +1 more source
Advanced Materials, EarlyView.ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu +8 more
wiley +1 more source