Results 161 to 170 of about 22,964,900 (284)

Economic Impact of Potential Outcome of the DDA

, 2011
Yvan Decreux, Lionel Fontagné, Lionel Fontagné   +2 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Commentary: Quantile treatment effect of zinc lozenges on common cold duration: A novel approach to analyze the effect of treatment on illness duration

Frontiers in Pharmacology, 2023
Jonas Moss
doaj   +1 more source

Authors' Reply: The Potential Outcome-Modification Influences Introduced by ESKD Life Plan on eGFR Slopes. [PDF]

J Am Soc Nephrol
Tabcheh AH, Boucquemont J, Pecoits-Filho R, Alencar De Pinho N, CKD-REIN Study Collaborators.   +4 more
europepmc   +1 more source

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

Journal of Neurology Neurosurgery & Psychiatry, 2009
C. Zampieri, A. Salarian, P. Carlson-Kuhta, K. Aminian, J. Nutt, F. Horak   +5 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Tumor regression grades: potential outcome predictor of locally advanced rectal adenocarcinoma after preoperative radiotherapy. [PDF]

World J Gastroenterol, 2015
Peng YF, Yu WD, Pan HD, Wang L, Li M, Yao YF, Zhao J, Gu J.   +7 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Potential outcome measures and trial design issues for multiple system atrophy

Movement Disorders, 2007
S. May, S. Gilman, B. Sowell, R. Thomas, M. Stern, A. Colcher, C. Tanner, Neng Huang, P. Novak, S. Reich, J. Jankovic, W. Ondo, P. Low, P. Sandroni, A. Lipp, Fred J Marshall, F. Wooten, C. Shults   +17 more
semanticscholar   +1 more source