Results 191 to 200 of about 5,371,394 (318)

Drivers and outcomes of value co-creation behaviour: Investigating the potential boundary conditions

, 2015
G Laud, IO Karpen, Rajendra Mulye, Kaleel Rahman   +3 more
openalex  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nanoparticle-based Drug Delivery for Pulmonary Tuberculosis: A Systematic Review on Enhanced Treatment outcomes, Cellular Uptake, Safety and Immunomodulatory Potential [PDF]

Malik Saim Jameel, Alveena Mushtaq Malik
openalex   +1 more source

Invited Perspective: The Potential of Potential Outcomes in Air Pollution Epidemiology

Environmental Health Perspectives, 2023
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Social protection: potential for improving HIV outcomes among adolescents [PDF]

, 2015
Lucie Cluver, Rebecca Hodes, Lorraine Sherr, F. Mark Orkin, Franziska Meinck, Patricia Lim Ah Ken, Natalia Elena Winder-Rossi, Jason Wolfe, Marissa Vicari   +8 more
openalex   +1 more source

Clarifying causal mediation analysis: Effect identification via three assumptions and five potential outcomes

, 2022
Trang Quynh Nguyen, Ian Schmid, Elizabeth L. Ogburn, Elizabeth A. Stuart   +3 more
openalex   +2 more sources

Noninvasive Monitoring and Potential for Patient Outcome

Journal of Cardiothoracic and Vascular Anesthesia, 2019
Susana, Vacas, Maxime, Cannesson
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology [PDF]

Ming Yang, Tiepeng Li, Shujin Guo, Kangping Song, Chuhui Gong, Ning Huang, Dejiang Pang, Hengyi Xiao   +7 more
openalex   +1 more source