Results 41 to 50 of about 2,428,925 (242)

Some theoretical foundations for the design and analysis of randomized experiments

Journal of Causal Inference
Neyman’s seminal work in 1923 has been a milestone in statistics over the century, which has motivated many fundamental statistical concepts and methodology.
Shi Lei, Li Xinran
doaj   +1 more source

Health reform in Mexico: governance and potential outcomes [PDF]

International Journal for Equity in Health, 2019
Adopting key mechanisms to restructure public policy in developing countries is a crucial political task. The strengthening of infrastructure of health services, care quality, monitoring and population health; all might contribute to assuring the functionality of a national system for health monitoring and care.
Jorge L. León-Cortés, Gustavo Leal Fernández, Héctor J. Sánchez-Pérez   +2 more
openaire   +3 more sources

A Tutorial in Bayesian Potential Outcomes Mediation Analysis [PDF]

Structural Equation Modeling: A Multidisciplinary Journal, 2017
Statistical mediation analysis is used to investigate intermediate variables in the relation between independent and dependent variables. Causal interpretation of mediation analyses is challenging because randomization of subjects to levels of the independent variable does not rule out the possibility of unmeasured confounders of the mediator to ...
Miočević, M., Gonzales, Oscar, Valente, Matthew, MacKinnon, David   +3 more
openaire   +3 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Prospective and retrospective causal inferences based on the potential outcome framework

Journal of Causal Inference
In this article, we discuss both prospective and retrospective causal inferences, building on Neyman’s potential outcome framework. For prospective causal inference, we review criteria for confounders and surrogates to avoid the Yule–Simpson paradox and ...
Geng Zhi, Zhang Chao, Wang Xueli, Liu Chunchen, Wei Shaojie   +4 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients. [PDF]

PLoS ONE, 2015
The sirtuin gene family has been linked with tumourigenesis, in both a tumour promoter and suppressor capacity. Information regarding the function of sirtuins in pancreatic cancer is sparse and equivocal.
Liane M McGlynn, Simon McCluney, Nigel B Jamieson, Jackie Thomson, Alasdair I MacDonald, Karin Oien, Euan J Dickson, C Ross Carter, Colin J McKay, Paul G Shiels   +9 more
doaj   +1 more source

Imputation approaches for potential outcomes in causal inference [PDF]

International Journal of Epidemiology, 2015
Background: The fundamental problem of causal inference is one of missing data, and specifically of missing potential outcomes: if potential outcomes were fully observed, then causal inference could be made trivially. Though often not discussed explicitly in the epidemiological literature, the connections between causal inference and missing data can ...
Daniel, Westreich, Jessie K, Edwards, Stephen R, Cole, Robert W, Platt, Sunni L, Mumford, Enrique F, Schisterman   +5 more
openaire   +2 more sources

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source