Results 101 to 110 of about 11,522,447 (298)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Concurrent strength and endurance training: the influence of dependent variable selection

open access: yes, 2003
Twenty-six active university students were randomly allocated to resistance (R, n 5 9), endurance (E, n 5 8), and concurrent resistance and endurance (C, n 5 9) training con-ditions.
Leveritt, Michael   +3 more
core  

The association between Dietary Oxidative Balance Score and muscle strength: NHANES 2011–2014

open access: yesFrontiers in Nutrition
BackgroundDietary Oxidative Balance Score (DOBS) is an indicator, and on muscle strength remains largely unexplored in existing literature. We aimed to investigate the potential association between DOBS and muscle strength, and to explore possible ...
Li Sun   +8 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

An investigation into the strength properties of reclaimed timber joists [PDF]

open access: yes
This research was designed to investigate the mechanical properties of timbers reclaimed from demolition, with the aim of generating a visual grade and model expression to grade these materials for structural reuse.
Smith, Michael J.
core  

Differences in Strength and Power Among Junior-High, Senior-High, College-Aged, and Elite Professional Rugby League Players

open access: yes, 2002
Ninety-five rugby league players ranging from junior high-school to elite professionals were compared for measures of strength and power. Strength was assessed by 1 repetition maximum bench press strength (1RM BP). Upper-body and lower-body power outputs
DANIEL BAKER, Baker, Daniel
core   +1 more source

Sink Strength Dynamics Based on Potential Growth and Carbohydrate Accumulation in Strawberry Fruit

open access: yesHortScience
Fruit size and sugar content are key determinants of fruit quality, influenced by environmental factors and agronomic practices and sink strength provided by the genetic potential.
Hiromi Nakai   +6 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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