Results 51 to 60 of about 11,522,447 (298)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Experimental Investigation on Shear Strength and Liquefaction Potential of Rubber-Sand Mixtures
The application of scrap tires as construction materials in civil engineering is one of the most promising ways to recycle this pollutant. The objective of this study was to investigate the shear strength and liquefaction potential of saturated rubber ...
Zhou Enquan, Wang Qiong
doaj +1 more source
Copernicus for monitoring European forests: strengths, challenges and potential
Copernicus is the European Union’s Earth Observation program, offering forest-related maps through its High-Resolution Layers (HRL). Corine Land Cover (CLC) and the Japan Aerospace Exploration Agency (JAXA) also provide map-based products on European forests.
Cesaretti, Lorenzo +3 more
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Rotator cuff strength assessments are valuable for monitoring throwing athlete injury and performance status. Portable technology enables "in-field" assessment and, therefore, increases utility.
Cronin, John B +2 more
core +1 more source
Introduction: Strength training is traditionally a vital component of motor culture and has been the focus of numerous studies which identify strength as a fundamental physical ability with a key role in athletic performance. Methods: The study aims to
M. Chipeva
doaj +1 more source

