Results 71 to 80 of about 11,522,447 (298)

The relationship between lower-body strength qualities and baserunning performance in high school aged baseball players : a pilot study

open access: yes, 2021
The purpose of this research was to determine 1) the relationship between lower-body strength qualities and baserunning and 2) the relationship between lower-body strength qualities and the time discrepancy between baserunning and linear sprints of the ...
Talpey, Scott   +2 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The strength of vulnerable positions: Financial hegemony and disruptive potential

open access: yesAnalyse de réseaux pour les sciences sociales, 2018
This article addresses the structural power of banks by analyzing the market for Leveraged Buy-Outs (LBOs) in France during the 2000s. It attempts to operationalize the concept of financial hegemony in an original way, working from the idea of point-vulnerability in a graph, introducing a method that can be used to model a network according to this ...
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Strength, Stiffness, and Microstructure of Wood-Ash Stabilized Marine Clay

open access: yes, 2020
The world's population is growing at a rapid pace, thus increasing the need for shelter, which, because of increased carbon emissions, is making our planet less habitable.
Ekinci, Abdullah   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Combined training (aerobic plus strength) potentiates a reduction in body fat but demonstrates no difference on the lipid profile in postmenopausal women when compared to aerobic training with a similar training load

open access: yes, 2015
The aim of this study was to verify the effects of aerobic and combined training on the body composition and lipid profile of obese postmenopausal women and to analyze which of these models is more effective after equalizing the training load. Sixty five
Papoti, Marcelo   +10 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

ELECTRIC FACTORS INFLUENCING THE COMPLEX EROSION PROCESSING BY INTRODUCING THE ELECTROLYTE THROUGH THE TRANSFER OBJECT [PDF]

open access: yesFiabilitate şi Durabilitate, 2014
The electric and electrochemical complex erosion processing is influenced by a great number of factors acting in tight interdependence and mutually influencing one another for achieving the stability of the processing process and achieving the final ...
Alin Nioata
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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