Results 61 to 70 of about 842,331 (261)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
JTSL (Jurnal Tanah dan Sumberdaya Lahan), 2019 Pati is one of the regency in Central Java Province which has a strategic position because it is crossed by the Java pantura line and also directly borders the Java Sea which is a trade route in Indonesia. In the case of the construction of an industrial
Agus Purwanto, I Iswandi
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Wildlife LettersABSTRACT The lynx, a nationally protected species in China, depends on prey such as roe deer and hares. Using 152 occurrence points and 12 environmental variables from Mohe, Heilongjiang, we applied the Biomod2 ensemble model to predict habitat suitability under climate change.
Binglian Liu +5 more
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Guangdong nongye kexue【Objective】Clarify the distribution pattern of suitable areas for Neoclytus acuminatus, a major invasive forest pest in China, and its response to future climate change as well as its potential invasion risk, so as to provide a scientific basis for ...
Xingyue XIANG +3 more
doaj +1 more source
Journal of Natural Resources and Environmental Management, 2019 Land suitability and availability is needed to be evaluated in Brebes Regency because the utilization of unsuitable land area is increasing to pursue high production targets as the impact of increased shallot demand. The objective of this research was to
Dina Martha Susilawati
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Geology, Ecology, and LandscapesAssessment of potential surface runoff harvesting sites is an important undertaking in a country like Ethiopia, where high spatial variability in rainfall, recurrent drought, and flash floods are common.
Chala Chimdessa +2 more
doaj +1 more source