Results 61 to 70 of about 14,383,600 (293)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Exact holography and black hole entropy in N=8 and N=4 string theory [PDF]
We compute the exact entropy of one-eighth and one-quarter BPS black holes in N=8 and N=4 string theory respectively. This includes all the N=4 CHL models in both K3 and T^4 compactifications.
Sub String Theory Cosmology and ElemPart +4 more
core +3 more sources
Harnack inequalities for hypoelliptic evolution operators: geometric issues and applications
We consider linear second order Partial Differential Equations in the form of "sum of squares of Hörmander vector fields plus a drift term" on a given domain.
Sergio Polidoro
doaj
A finite element method for exterior interface problems
A procedure is given for the approximate solution of a class of two-dimensional diffraction problems. Here the usual inner boundary conditions are replaced by an inner region together with interface conditions.
R. C. Maccamy, S. P. Marin
doaj +1 more source
A novel technique for the calculation of post-stall aerodynamic coefficients for S809 airfoil [PDF]
In the autumn of 2000, the National Renewable Energy Laboratory (NREL) organised a 'blind comparison', in which wind turbine research centres worldwide were asked to provide stationary aerodynamic loads for the wind turbine Phase VI and aerodynamic ...
Arramach J. +3 more
doaj
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The ultra-high-speed aerodynamically alleviated marine vehicle (AAMV) is a high-performance vessel that combines a hydrodynamic configuration and an aerodynamic wing to reduce wave-making resistance during the high-speed planing phase.
Yani Song, Xiaoxu Du, Yuli Hu
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

