Results 231 to 240 of about 2,210,830 (305)

The Economic Costs of Congenital Hearing Loss in a South African Cohort. [PDF]

Health Serv Insights
Tombe-Mdewa W, Storbeck C, Young A, Moolla A, Goldstein S, Thsehla E.   +5 more
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Direct and Indirect Costs of Cancer in Adult Population of Poland in the Period 2021-2023. [PDF]

Cancers (Basel)
Gąska I, Czerw A, Pajewska M, Partyka O, Charkiewicz D, Deptała A, Badowska-Kozakiewicz A, Sygit K, Dziubek I, Wojtyła-Buciora P, Drobnik J, Pobrotyn P, Waśko-Czopnik D, Sowiński T, Pobrotyn J, Wiatkowski A, Bandurska E, Ciećko W, Grochans E, Cybulska AM, Schneider-Matyka D, Rachubińska K, Czapla T, Kamecka K, Kozlowski R.   +24 more
europepmc   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Smoking-attributable ischemic heart disease burden in China from 1990 to 2021 and projections to 2036: A retrospective analysis and forecasting study. [PDF]

Tob Induc Dis
Xu D, Yang Z, Yao W, Wang X.
europepmc   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Demographic Factors and Trends Associated with Mortality After AIDS Diagnosis in Puerto Rico. [PDF]

Infect Dis Rep
Burgos-Barreto G, Reyes D, Tremblay RL.
europepmc   +1 more source

Does Allowing Law-Abiding Citizens to Carry Concealed Handguns Save Lives? [PDF]

, 2011
Lott, John R., Jr.
core   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Pancreatic cancer in China: the analysis of cancer mortality and burden in China, 2008-2021. [PDF]

BMC Cancer
Ning Y, Mu J, Zhang Z, Zhang Y, Tang C.
europepmc   +1 more source