Results 251 to 260 of about 2,210,830 (305)

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

What can administrative registers tell us about the widening in life expectancy gap in people with mental disorders? [PDF]

BJPsych Open
Plana-Ripoll O, Formánek T, Momen NC.
europepmc   +1 more source

Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems

Advanced Science, EarlyView.
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li, Mingyu Xie, Nan Jia, Li‐Dong Mo, Qiang Yu, Fanjiang Zeng, Xiangyi Li   +6 more
wiley   +1 more source

The decline of 'Deaths of Despair' in Italy: unveiling this phenomenon in a new context. [PDF]

Popul Health Metr
Lanfiuti Baldi G, Nigri A, Trias-Llimós S, Barbi E.   +3 more
europepmc   +1 more source

Valuing risks to life and health: towards consistent transfer estimates in the European Union and accession states [PDF]

, 2000
Pearce, D.W.
core  

The broad societal value of pembrolizumab for women's cancer in Canada. [PDF]

Future Oncol
Brook E, Patterson K, Wijenayake N, Madin-Warburton M, Mishkin K, Meilleur MC, Davies A, Young K.   +7 more
europepmc   +1 more source

To splint or not to splint? Do thermoplastic hand splints maintain passive range of movement following severe acquired brain injury in a long-term care setting? [PDF]

Hand Ther
Blacker D, Cassim A.
europepmc   +1 more source

Temporal trends in associations between social drivers and life-years lost in newly diagnosed atrial fibrillation in Denmark, 2000-22: a nationwide cohort study. [PDF]

Lancet Public Health
Vinter N, Johnsen SP, Lip GYH, Trinquart L, Frost L, Benjamin EJ.   +5 more
europepmc   +1 more source

Mitigating Future Respiratory Pandemics in Low-, Middle- and High-Income Countries: A Modelling Study of Health, Economic and Educational Losses

Doohan P, Johnson R, Løchen A, Morgenstern C, Haw D, Sabino A, Patouillard E, Forchini G, Hauck K.   +8 more
europepmc   +1 more source

Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV.

JAMA Netw Open
Smith KC, Brown C, Hyle EP, Zafarnejad R, Brown TT, Freedberg KA, Erlandson KM, Losina E.   +7 more
europepmc   +1 more source