Results 51 to 60 of about 752,443 (346)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The presence of obesity and metabolic syndrome is strongly linked with chronic kidney disease (CKD), but the mechanisms responsible for the association are poorly understood.
Ana Andres-Hernando +8 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
AN ECONOMIC EVALUATION OF THE EFFICIENCY OF OPERATING AGRICULTURAL MACHINES IN PRODUCTION OF WHEAT [PDF]
Agricultural sector is considered to be one of the most important sectors in the Egyptian economy that contributes greatly in the national income. Therefore, the state pays great intention to the agricultural sector concerning all developmental aspects ...
Aziza Hussein +3 more
doaj +1 more source
Micro-pound extended range thrust stand Patent [PDF]
Micro-pound extended range thrust stand for small rocket ...
Stark, K. W.
core +1 more source
Development of the health and economic consequences of smoking interactive model [PDF]
Objective-To describe the health and economic consequences of smoking model, a user friendly, web based tool, designed to estimate the health and economic outcomes associated with smoking and the benefits of smoking cessation.
Godfrey, C +4 more
core +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
"So many people going the other way" : an examination of the moral strategy of language usage in five novels by Janet Frame : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University [PDF]
The title quotation is from Janet Frame's novel, Living in the Maniototo (72). Abbreviations and editions of the five primary sources referred to in the text are as follows: EA The Edge of the Alphabets London: W.H. Allen & Co., 1962.
Pound, Lynette Ruth
core
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

