Results 81 to 90 of about 5,842 (259)

A Phase I study of the pharmacokinetics (PK), bioavailability, dose proportionality, safety, and tolerability of topiramate injection compared to Oral topiramate in healthy adult participants

Epilepsia, EarlyView.
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye, James C. Cloyd, Bernard D. King, Lisa D. Coles   +3 more
wiley   +1 more source

On the Trail of Creativity: Dimensionality of Divergent Thinking and Its Relation With Cognitive Abilities, Personality, and Insight

European Journal of Personality, EarlyView., 2020
Abstract Divergent thinking (DT) is an important constituent of creativity that captures aspects of fluency and originality. The literature lacks multivariate studies that report relationships between DT and its aspects with relevant covariates, such as cognitive abilities, personality traits (e.g. openness), and insight. In two multivariate studies (N 
S. Weiss, D. Steger, Y. Kaur, A. Hildebrandt, U. Schroeders, O. Wilhelm, Christian Kandler   +6 more
wiley   +1 more source

Cross‐Entropy of Power Spectral Density Function: A Modal Identification Framework

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT The power spectral density (PSD) function of measured structural response contains a significant amount of information, including the modal parameters (natural frequencies, damping ratios). Output‐only system identification or modal identification technique can be used for extracting such modal parameters from the measured response or its ...
Su‐Hong Kim, Jae‐Seung Hwang, Dae‐Kun Kwon, Ahsan Kareem   +3 more
wiley   +1 more source

Analytical Framework for System‐Level Fragility Surfaces of Reinforced Concrete Bridges Under Mainshock‐Aftershock Sequences

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Conventional single intensity measure (IM) fragility approaches with simplified component dependency assumptions overlook the progressive damage accumulation and evolving inter‐component correlations that govern system behavior under mainshock‐aftershock (MSAS) loading.
Muhammad Rashid, Mayuko Nishio
wiley   +1 more source

Surrogate‐Based Time‐Continuous Seismic Fragility Assessment of Corrosion‐Deteriorated Reinforced Concrete Bridges Under Climate Change

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Seismic fragility assessment of reinforced concrete (RC) bridges exposed to corrosive environments must reliably capture time‐dependent deterioration impacts. Climate change compounds this challenge through nonstationary temperature and humidity variations that accelerate bridge corrosion.
Yexiang Yan, Yazhou Xie
wiley   +1 more source

Resource allocation and growth strategies in a multi‐plant firm: Kanegafuchi Spinners in the early 20th century

Strategic Management Journal, EarlyView., 2023
Abstract Research Summary Using detailed plant‐ and individual‐level data from a major Japanese cotton spinning company in the early 20th century, we examine the within‐firm allocation of skilled human capital in conjunction with investment in physical capital, accompanying the firm's evolving strategic priorities.
Shotaro Yamaguchi, Serguey Braguinsky, Tetsuji Okazaki, Takenobu Yuki   +3 more
wiley   +1 more source

Effectiveness of Elastomeric Bearings in Reducing Pounding Effects between Reinforced Concrete Buildings under Seismic Condition

Civil Engineering Dimension
This study investigates seismic pounding hazards between adjacent reinforced concrete buildings in East Java, particularly those designed under older regulations without pounding considerations.
M. Riski Audri Rahman, Ashar Saputra, Iman Satyarno   +2 more
doaj   +1 more source

Streamlining Hospital Planning: A User‐Friendly Decision Support Tool for Enhanced Healthcare Delivery

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Healthcare providers worldwide face challenges in maintaining a delicate balance between rising demand and limited resources. Decision‐makers often struggle with planning and implementing new services, leading to costly consequences and hindering efficiency, patient outcomes, and staff well‐being. Current systems lack a comprehensive modelling
Eren Demir
wiley   +1 more source

Seismic Pounding between Adjacent Building Structures

Electronic Journal of Structural Engineering, 2006
Investigations of past and recent earthquake damage have illustrated that the building structures are vulnerable to severe damage and/or collapse during moderate to strong ground motion.
Shehata E. Abdel Raheem
doaj  

Brexit and Its Impact on EU Financial Markets

International Journal of Finance &Economics, EarlyView.
ABSTRACT We investigate the impact of Brexit on volatility spillovers across the EU countries. We introduce a Brexit intensity measure that assigns an intensity score reflective of the financial markets' reaction to the events that occurred as Brexit negotiations began to unfold.
Marwan Izzeldin, Gulnur Muradoglu, Vasileios Pappas, Sheeja Sivaprasad   +3 more
wiley   +1 more source