Results 141 to 150 of about 1,989,813 (313)
Data and Definitions Supplement: 2009 Report on Illinois & Chicago Region Poverty [PDF]
, 2009 This supplement to the 2009 Report on Illinois Poverty and the Report on Chicago Region Poverty contains: the county well-being index, which provides a standard for localities to use as they monitor their county's progress on poverty issues; local data ...
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
2007 Report on Illinois Poverty [PDF]
, 2007 This seventh annual Report on Illinois Poverty illustrates that there are many indications Illinois families are experiencing significant hardship. Over one third of Illinoisans in poverty are children, disparities in income and wealth are widening ...
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Overall Declines in Child Poverty Mask Relatively Stable Rates Across States [PDF]
, 2016 In this brief, authors Andrew Schaefer, Jessica Carson, and Marybeth Mattingly use Census data released on September 15, 2016, from the American Community Survey--the only regular source for estimating yearly child poverty rates at, and below, the state ...
Carson, Jessica A. +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Changing Spatial Concentration of America\u27s Rural Poor Population [PDF]
, 2007 This paper documents changing patterns of concentrated poverty in nonmetro areas. Data from the Decennial U.S. Census Summary Files show that poverty rates—both overall and for children—declined more rapidly in nonmetro than metro counties in the 1990s ...
Johnson, Kenneth M., Lichter, Daniel T.
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2011 Lorenzo Nosotti +5 more
doaj +1 more source