Results 181 to 190 of about 2,092,140 (361)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Trends in Absolute Poverty in Pakistan: 1990-91 and 2001 [PDF]
Poverty, defined comprehensively as absence of options to shape one’s life according to one’s own preferences, comes closer to the concept of human development as presented in UNDP’s Human Development Reports.
Sarfraz K. Qureshi, Talat Anwar
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Cancer Burden in Persistent Poverty Areas across the Cancer Continuum: A Scoping Review to Identify Gaps and Opportunities for Future Research. [PDF]
Cancer Epidemiol Biomarkers PrevHallgren E +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The paper presents the first major update of the international"$1 a day"poverty line, first proposed in 1990 for measuring absolute poverty by the standards of the world's poorest countries.
Chen, Shaohua +2 more
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Evaluating screening and intervention for poverty in family practice settings in Saskatchewan in the context of the COVID-19 pandemic. [PDF]
Prim Health Care Res DevManalac L +4 more
europepmc +1 more source
Poverty: legal and constitutional implications for human rights enforcement in Nigeria
, 2009 Charles Olufemi Adekoya, Eva Brems
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Determinants of Poverty during Transition: Household Survey Evidence from Ukraine [PDF]
The paper analyzes the incidence, the severity and the determinants of household poverty in Ukraine during transition using two comparable surveys from 1996 and 2004.
Brück, Tilman +3 more
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