Results 131 to 140 of about 5,300,961 (303)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Ending child poverty: policy statement on child poverty
, 2005 • Child poverty has fallen significantly over the past decade. However, the number of families with children in relative income poverty (sometimes referred to as 'at-risk-of-poverty') has remained relatively static over this time.
Combat Poverty Agency
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Growth, Distribution, and Poverty in Africa : Messages from the 1990s
, 2002 This book synthesizes, and elaborates on the results of a series of country studies, completed under the Poverty Dynamics in Africa Initiative, organized by the Africa Region of the Bank.
Demery, Lionel +2 more
core +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Using rights-based approaches to tackle poverty: funded intitatives 2005
, 2006 Combat Poverty Agency believes that tackling poverty involv'es the recognition of economic, social and cultural rights, the eradication of discrimination and respect for diversity.
Combat Poverty Agency
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FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Submission on the development of the new National Drugs Strategy 2007 - 2016
, 2008 The Combat Poverty Agency is a state advisory agency developing and promoting evidence-based proposals and measures to combat poverty in Ireland. One of the functions of Combat Poverty is to advise the government on all aspects of social and economic ...
Combat Poverty Agency (CPA)
core
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Tackling health inequalities locally
, 2009 In keeping with the goals of its Strategic Plan, Combat Poverty launched the Building Healthy Communities (BHC) programme in 2005 to help address health inequalities in disadvantaged areas by mobilising community responses, exploring the links ...
Combat Poverty Agency (CPA)
core