Results 71 to 80 of about 34,360 (258)

Evaluation of the Performance of K-means and Bisecting K-means in Clustering Indonesian Regions using Poverty Data [PDF]

E3S Web of Conferences
Clustering regions in Indonesia based on poverty data is essential for developing targeted policies. A key challenge is determining the optimal number of clusters to accurately reflect regional disparities. This study compares the Bisecting K-means and K-
Bantala Dhea Cindera, Rosa Paulina Heruningsih Prima   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Zoning and spatial analysis of poverty in urban areas (Case Study: Sabzevar City-Iran)

Journal of Urban Management, 2019
The present descriptive-analytical study employs a survey research method, documentary technique, and applied-developmental research design to zone the 18 neighborhoods of Sabzevar City in terms of urban poverty indicators.
Rahman zandi, Mehdi Zanganeh, Ebrahim Akbari   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of Poverty Determinant Factors Based on Indonesian Province Data 2017-2023

Indonesian Interdisciplinary Journal of Sharia Economics
This study aims to identify factors contributing to poverty in Indonesia and map the distribution of poverty levels. The data used in this study are secondary data sourced from the Central Statistics Agency (BPS).
Nisrina Isnaini, Lukman Hakim, Mulyanto Mulyanto   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mapping Fuel Poverty in Portugal

Energy Procedia, 2016
Abstract We defined a novel methodology to assess the potential fuel poverty of residential dwellings at LAU2 level combining data on income, level of education, unemployment rate, and number of inhabitants above 65 years old, with both the space heating and cooling gap estimated per household typology.
Simoes, Sofia G., Gregório, Vera, Seixas, Júlia   +2 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source