Results 111 to 120 of about 3,813,329 (294)
Developing a Local anti-poverty and social inclusion strategy: A guide [PDF]
, 2007 The EU member states, including Ireland, recognise that poverty and social exclusion are critical issues they must tackle. In 1997 the Irish Government, in consultation with the social partners, community and voluntary sector and other stakeholders ...
Combat Poverty Agency (CPA)
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Drivers of household poverty in Somaliland: empirical evidence
Cogent Social SciencesDespite global progress in poverty reduction, poverty remains a persistent challenge in Somaliland. This study aims to identify the factors associated with household poverty in Somaliland, addressing a notable gap in the literature on de facto states ...
Hamse Abdiwahab. Abdilahi +1 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Household Poverty Dynamics in Malawi [PDF]
This paper’s goal is to identify the sources of expenditure and poverty dynamics among Malawian households between 1998 and 2002 and to model poverty transitions in Malawi using a bivariate probit model with endogenous selection to address the "initial ...
Bokosi, Fanwell Kenala
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The mediating effects of adulthood socioeconomic status and social support on adulthood impacts of childhood poverty in Japan [PDF]
Previous studies have provided evidence of the lasting impact of low socioeconomic status (SES) in childhood on adulthood health. However, the mediating pathway that links them is still under debate.
Umeda, Maki, Oshio, Takashi, Fujii, Mayu
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Asset versus consumption poverty and poverty dynamics in the presence of multiple equilibria in rural Ethiopia [PDF]
Effective poverty reduction programs require careful measurement of poverty status. Several studies have shown conceptually that assets reflecting productive capacity form a more robust basis for identifying the poor than do flow variables such as ...
Winter-Nelson, Alex +1 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source